Research on the formation criterion of supported bilayer lipid membranes for biosensors development

机译：用于生物传感器开发的支撑双层脂质膜形成标准的研究

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Supported Bilayer Lipid Membrane (s-BLM) is a kind of mimicking biomembrane in vitro. The s-BLM was widely applied as a cell membrane model and sensing material of biosensors and biomolecular devices. An electrode based on s-BLM modified with valinomycin was fabricated. Utilizing Cyclic Voltammetry (CV), the influence of temperature on the formation of s-BLM on the top section of the electrode was investigated. The results show that the BLM formed on the top of stainless electrode occurs "phase transition" around 39 Celsius degree. This alters the CV characteristics of BLM. The "phase transition temperature" can be as a new judgment method of the s-BLM configuration.

机译：支持的双层脂质膜（s-BLM）是一种体外模拟生物膜的方法。 s-BLM广泛用作细胞膜模型和生物传感器和生物分子设备的传感材料。制备了以缬氨霉素修饰的基于s-BLM的电极。利用循环伏安法（CV），研究了温度对电极顶部s-BLM形成的影响。结果表明，在不锈钢电极顶部形成的BLM在39摄氏度左右发生“相变”。这会改变BLM的CV特性。 “相变温度”可以作为s-BLM结构的新的判断方法。

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来源
《ICMIT 2005: Mechatronics, MEMS, and Smart Materials》|2005年|P.60401R.1-60401R.5|共5页
会议地点 Chongqing(CN)
作者
Shengping Liu; Yunlong Wei; Guoming Chen;
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作者单位

Institute of Medical Engineering College of Bioengineering Chongqing Institute of Technology, 400050, China;

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会议组织
原文格式 PDF
正文语种 eng
中图分类信息处理（信息加工）;
关键词
lipid bilayers; membranes; biosensor; formation criterion; phase transition temperature;

机译：脂质双层；膜；生物传感器；形成准则；相变温度;

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4. Research on the formation criterion of supported bilayer lipid membranes for biosensors development [C] . Shengping Liu, Yunlong Wei, Guoming Chen International Conference on Mechatronics and Information Technology: Mechatronics, MEMS, and Smart Materials . 2005

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5. Bilayer lipid membrane (BLM) integration into microfluidic platforms with application toward BLM-based biosensors. [D] . Hromada, Louis Paul, Jr. 2007

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机译：1P225在具有微孔的聚合物膜上形成脂质双层膜的形成，并将蛋白质重建为负载膜

Research on the formation criterion of supported bilayer lipid membranes for biosensors development

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