• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>IEEE International Conference on Plasma Science >The Selective Effect of Plasma Activated Media on Cells
【24h】

The Selective Effect of Plasma Activated Media on Cells

机译：血浆活化培养基对细胞的选择性作用

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

. However, much less is known about the effects of PAM on non-cancerous cells. We report on the effects of PAM on the viability and morphological characteristics of non-cancerous epithelial cells. In a comparative study, we present the effects of PAM on the viability of cancerous cells. In this research, non-cancerous MDCK (Madin-Darby Canine Kidney) cells and SCaBER (from a bladder squamous cell carcinoma) cells were used. It was found that there is an optimum dose of PAM (LTP exposure time) to suppress viability of cancer cells significantly while inducing minimum damage to normal cells. Finally, molecular beacons were also employed to investigate the effects of direct LTP treatment on DNA. Molecular beacons are single strand DNA oligonucleotides which adopt a stem-and-loop shape. Our results indicate that plasma exposure causes dose-dependent DNA strand breaks in the molecular beacons.
机译：。但是，关于PAM对非癌细胞的作用了解的很少。我们报告了P​​AM对非癌性上皮细胞活力和形态特征的影响。在一项比较研究中，我们介绍了PAM对癌细胞活力的影响。在这项研究中，使用了非癌性MDCK（Madin-Darby犬肾）细胞和SCaBER（来自膀胱鳞状细胞癌）细胞。发现存在最佳剂量的PAM（LTP暴露时间）以显着抑制癌细胞的生存力，同时对正常细胞的损害最小。最后，分子信标也被用于研究直接LTP处理对DNA的影响。分子信标是采用茎环形状的单链DNA寡核苷酸。我们的结果表明，血浆暴露会导致分子信标中剂量依赖性DNA链断裂。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号