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首页> 外文会议>Conference on optical interactions with tissue and cells >Photothermal effect of infrared lasers on ex vivo lamb brain tissues
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Photothermal effect of infrared lasers on ex vivo lamb brain tissues

机译：红外激光对离体羔羊脑组织的光热效应

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Here, the most suitable infrared laser for a neurosurgery operation is suggested, among 1940-nm thulium fiber, 1470-nm diode, 1070-nm ytterbium fiber and 980-nm diode lasers. Cortical and subcortical ex-vivo lamb brain tissues are exposed to the laser light with the combinations of some laser parameters such as output power, energy density, operation mode (continuous and pulsed-modulated) and operation time. In this way, the greatest ablation efficiency associated with the best neurosurgical laser type can be defined. The research can be divided into two parts; pre-dosimetry and dosimetry studies. The former is used to determine safe operation zones for the dosimetry study by defining coagulation and carbonization onset times for each of the brain tissues. The latter is the main part of this research, and both tissues are exposed to laser irradiation with various energy density levels associated with the output power and operation time. In addition, photo-thermal effects are compared for two laser operation modes, and then coagulation and ablation diameters to calculate the ablation efficiency are measured under a light microscope. Consequently, results are compared graphically and statistically, and it is found that thulium and 1470-nm diode lasers can be utilized as subcortical and cortical tissue ablator devices, respectively.
机译：在这里，建议使用最适合神经外科手术的红外激光器，包括1940 nm ul光纤，1470 nm二极管，1070 nm fiber光纤和980 nm二极管激光器。皮质和皮质下的离体羔羊脑组织暴露于具有一些激光参数（例如输出功率，能量密度，操作模式（连续和脉冲调制）和操作时间）的激光下。这样，可以定义与最佳神经外科激光类型相关的最大消融效率。研究可以分为两个部分。剂量前和剂量学研究。前者用于通过定义每个脑组织的凝固和碳化开始时间来确定剂量学研究的安全操作区域。后者是本研究的主要部分，两个组织都受到与输出功率和操作时间相关的各种能量密度水平的激光照射。另外，比较了两种激光操作模式的光热效应，然后在光学显微镜下测量凝结和烧蚀直径以计算烧蚀效率。因此，对结果进行图形和统计比较，发现th和1470-nm二极管激光器可以分别用作皮层下和皮层组织消融器。

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