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首页> 外文会议>Conference on optical interactions with tissue and cells >Highlighting the nuances behind interaction of picosecond pulses with human skin:Relating distinct laser-tissue interactions to their potential in cutaneous interventions
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Highlighting the nuances behind interaction of picosecond pulses with human skin:Relating distinct laser-tissue interactions to their potential in cutaneous interventions

机译：突出皮秒脉冲与人皮肤相互作用背后的细微差别：将明显的激光-组织相互作用与其在皮肤干预中的潜力联系起来

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摘要

In recent years, several commercial systems relying on picosecond pulses have been introduced into the field of cutaneous interventions. In parallel with this development, a somewhat distinct research prototype also operating in the picosecond regime was described in literature. Albeit both market-available products and the investigational device employ laser beams of nearly the same pulse duration and were reported to cause laser-induced optical breakdown (LIOB), they are different in terms of wavelength, applied fluence, laser beam quality, optical architecture and related focusing optics, resulting in different histo-morphological features (such as e.g. lesion size, location, expression of collagen). Understanding the differences between these systems in relation to implications for clinical results raises a need in highlighting the nuances behind interaction of picosecond pulses with biological tissue. To achieve this, we accentuate the interplay of irradiance levels of picosecond pulses in W/cm2, absorption properties of a target tissue at a wavelength of a light source and resulting interaction mechanisms with biological object. We also relate these nuances to potential consequences for cutaneous interventions.
机译：近年来，几种依赖于皮秒脉冲的商业系统已经被引入皮肤介入领域。与这一发展同时，文献中描述了在皮秒状态下运行的某种不同的研究原型。尽管市场上销售的产品和研究设备均使用几乎相同的脉冲持续时间的激光束，据报​​道会引起激光诱导的光击穿（LIOB），但它们在波长，施加的注量，激光束质量，光学结构方面有所不同以及相关的聚焦光学器件，导致不同的组织形态特征（例如病变大小，位置，胶原蛋白表达）。了解这些系统之间的差异以及对临床结果的影响，因此需要强调皮秒脉冲与生物组织相互作用背后的细微差别。为了实现这一点，我们强调了皮秒脉冲的辐照度水平（W / cm2），目标组织在光源波长处的吸收特性以及与生物物体的相互作用机制之间的相互作用。我们还将这些细微差别与皮肤干预的潜在后果联系起来。

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