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Neurologically induced skin perfusion changes using optoelectronic devices: aims and results of an Indo-German project

机译:使用光电设备的神经学引起的皮肤灌注变化:印德项目的目的和结果

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Abstract: In recent years investigation and understanding of the interaction between brain activity and human hemodynamics is receiving much attention. Such investigations are generally confined to few select premier research institutions where expensive and sophisticated facilities like PET, NMRI, etc. are available. Actual advancement in optoelectronics and computer technology have accelerated the development of new measuring systems and methodologies for use in this medical field. Specifically, transcutaneous assessment of skin perfusion changes (blood volumetric measurement) through optical sensor based Photoplethysmography (PPG) has rapidly gained an important role. This basically noninvasive measuring procedure is devoid of harmful radiation and ionizing phenomena, simple in construction and connection to the measuring setup and is easy to use in all areas of human body. The relatively low cost of these sensors have resulted in their use in varied medical fields for extensive clinical applications. In the past, the application of PPG had been limited by technical difficulties involving calibration of the data. The development of quantitative PPG technique based on computer-aided data processing has removed this obstacle. In co-operation between Indian Institute of Technology at Chennai and Aachen University of Technology an Indo-German Project was initiated in 1996 for advanced studies in this research area. Measuring system design, experimental details and some preliminary results obtained so far within the framework of this project are presented in this paper. From the investigations carried out so far using the PPG sensors in conjunction with breathing sensors, it has been possible to monitor the 0.125 to 0.15 Hz rhythms in the arterial volumetric changes and to study the influence of breathing on them. These rhythms, which according to medical experts have relevance to psychosomatic conditions e.g. stress or relaxation, can also be addressed to by ancient Indian practices like yoga and meditation. !12
机译:摘要:近年来,人们对脑活动与人类血液动力学之间相互作用的研究和理解受到了广泛关注。这样的研究通常仅限于少数选择的主要研究机构,那里没有昂贵而复杂的设施,如PET,NMRI等。光电技术和计算机技术的实际发展加速了用于该医学领域的新测量系统和方法的发展。具体地,通过基于光学传感器的光电容积描记术(PPG)的皮肤灌注变化的透皮评估(血液体积测量)已迅速获得重要作用。这种基本无创的测量程序无有害辐射和电离现象,结构简单,与测量装置的连接简单,易于在人体的所有区域使用。这些传感器的相对较低的成本导致它们在广泛的临床应用中用于各种医学领域。过去,PPG的应用受到涉及数据校准的技术难题的限制。基于计算机辅助数据处理的定量PPG技术的发展消除了这一障碍。在钦奈印度理工学院和亚琛工业大学之间的合作下,印度-德国项目于1996年启动,旨在对该领域进行高级研究。本文介绍了该项目框架内的测量系统设计,实验细节和一些初步结果。从迄今为止使用PPG传感器和呼吸传感器进行的调查中,可以监测动脉容积变化中0.125至0.15 Hz的节律并研究呼吸对其的影响。根据医学专家的说法,这些节律与心身状况有关,例如古老的印度习俗,例如瑜伽和冥想,也可以解决压力或放松。 !12

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