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Coherent Bremsstrahlung Used for Digital Subtraction Angiography

机译:相干Bre致辐射用于数字减影血管造影

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Digital subtraction angiography (DSA), also known as Dichromography, using synchrotron radiation beams has been developed at Stanford University (R. Hofstadter) and was subsequently taken over at the Brookhaven Synchrotron and later at Hamburg (HASYLAB) [see, e.g., W.R. Dix, Physik in unserer Zeit. 30 (1999) 160]. The imaging of coronary arteries is carried out with an iodine-based contrast agent which need not be injected into the heart. The radiation must be monochromatized and is applied above and below the K-edge of iodine (33.16 keV), with a subsequent digital subtraction of the two images. Monochromatization of the synchrotron radiation causes a loss of intensity of 10~(-3). We propose instead the use of coherent bremsstrahlung [see, e.g., A.W. Saenz and H. UEberall, Phys. Rev. B25 (1982) 448] which is inherently monochromatic, furnishing a flux of 10~(12) photon/sec. This requires a 10-20 MeV electron linac which can be obtained by many larger hospitals, eliminating the scheduling problems present at synchrotrons.rnThe large, broad incoherent bremsstrahlung background underlying the monochromatic spike would lead to inadmissible overexposure of the patient. This problem can be solved with the use of Kumakhov's capillary optics [see e.g., S.B.Dabagov, Physics-Uspekhi 46 (2003) 1053]: the low-energy spiked radiation can be deflected towards the patient, while the higher energy incoherent background continues forward, avoiding the patient who is placed several meters from the source.
机译:斯坦福大学(R. Hofstadter)已开发出使用同步加速器辐射束的数字减影血管造影术(DSA),也称为双色谱法,随后被布鲁克海文同步加速器接管,后来又被汉堡(HASYLAB)接管[参见,例如WR Dix ,Physik处于无效的Zeit中。 30(1999)160]。冠状动脉的成像是基于碘的造影剂进行的,不需要注入心脏。辐射必须被单色化,并施加在碘的K边缘上方和下方(33.16 keV),随后将两个图像进行数字减法。同步辐射的单色化导致强度损失10〜(-3)。我们建议改用相干的ms致辐射[例如,参见A.W. Saenz和H.UEberall,物理学。 Rev. B25(1982)448]本质上是单色的,提供10〜(12)光子/秒的通量。这就需要10-20 MeV电子直线加速器,许多大型医院都可以得到,避免了同步加速器中存在的调度问题。单色尖峰下面的宽广,不连贯的致辐射背景会导致患者过度暴露。该问题可以通过使用库玛霍夫的毛细管光学器件来解决[参见,例如,SBDabagov,Physics-Uspekhi 46(2003)1053]:低能量的尖峰辐射可以偏向患者,而高能量的非相干背景继续向前,避免将患者放在离源头几米远的地方。

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