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Novel Synthesis Method and Biomedical Applications of Doped and In doped Hydroxyapatites and Fluoroapatites

机译:掺杂和掺杂的羟基磷灰石和氟磷灰石的新型合成方法及其生物医学应用

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摘要

An essentially new method of synthesis of apatite - based materials in saline melts at moderate temperatures (350-700℃) is developed. The method combines in itself the advantages of the ways of hyper-thermal hydrolysis (a "dry" method) and precipitation from aqueous solutions (a "wet" method). As a reaction media the melts of the equimolar NaCl-KCl system as well as eutectics of the NaNO_3 - KNO_3 composition were used. Silver-containing and Palladium-containing apatites were obtained. Those can be used as a materials with antimicrobial and antitumor properties. The obtained materials were identified with a method of the X-ray diffraction phase analysis, and IR - spectroscopy. The developed method of synthesis of the biocompatible nanoscale materials and composites from them is a rather effective and accessible way to practical usage in dentistry, orthopaedics and other areas of medicine.
机译:开发了一种基本的新方法,可在中等温度(350-700℃)下在盐水熔体中合成磷灰石基材料。该方法本身结合了超高温水解(“干”方法)和从水溶液中沉淀(“湿”方法)的优点。作为反应介质,使用了等摩尔NaCl-KCl体系的熔体以及NaNO_3-KNO_3组成的低共熔物。获得了含银和含钯的磷灰石。这些可以用作具有抗微生物和抗肿瘤特性的材料。用X射线衍射相分析和IR光谱法鉴定获得的材料。从生物合成的纳米级材料及其复合材料开发的合成方法是在牙科,整形外科和其他医学领域中实际应用的相当有效且容易获得的方法。

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