Oncology in Vivo Data Integration for Hypothesis Generation

机译：用于假说生成的体内肿瘤数据集成

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AstraZeneca's Oncology in vivo data integration platform brings multidimensional data from animal model efficacy, pharmacokinetic and pharmacodynamic data to animal model profiling data and public in vivo studies. Using this platform, scientists can cluster model efficacy and model profiling data together, quickly identify responder profiles and correlate molecular characteristics to pharmacological response. Through meta-analysis, scientists can compare pharmacology between single and combination treatments, between different drug scheduling and administration routes.

机译：阿斯利康的Oncology体内数据集成平台将多维数据从动物模型功效，药代动力学和药效动力学数据引入动物模型分析数据和公共体内研究中。使用该平台，科学家可以将模型功效和模型分析数据聚集在一起，快速识别响应者概况，并将分子特征与药理反应相关联。通过荟萃分析，科学家们可以比较单一疗法和联合疗法之间，不同药物调度和给药途径之间的药理作用。

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来源
《International symposium on integrative bioinformatics, 8th annual meeting》|2012年|126-134|共9页
会议地点 Hangzhou(CN)
作者
Jia Wei; Ming Chen;
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作者单位

AstraZeneca Innovation Center China, RD Information China, Building 7, No.898 Halei Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China;

AstraZeneca Innovation Center China, RD Information China, Building 7, No.898 Halei Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China;

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原文格式 PDF
正文语种 eng
中图分类生物信息论;
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专利

1. Oncology In Vivo Data Integration for Hypothesis Generation [J] . Jia Wei, Ming Chen Journal of Integrative Bioinformatics . 2012,第2期

机译：体内肿瘤数据集成以生成假设
2. Personalized Oncology Suite: integrating next-generation sequencing data and whole-slide bioimages [J] . Andreas Dander, Matthias Baldauf, Michael Sperk, BMC Bioinformatics . 2014,第1期

机译：个性化肿瘤套件：整合下一代测序数据和全幻灯片生物图像
3. The integration of cancer survivorship training in the curriculum of hematology/oncology fellows and radiation oncology residents [J] . ShayneM., CulakovaE., MilanoM.T., Journal of cancer survivorship: research and practice . 2014,第2期

机译：将癌症幸存者培训纳入血液学/肿瘤学进修人员和放射肿瘤学住院医师课程
4. Oncology in Vivo Data Integration for Hypothesis Generation [C] . Jia Wei, Ming Chen International symposium on integrative bioinformatics . 2012

机译：虚拟生成的体内数据集成中的肿瘤学
5. Data and -Omics-Driven Approaches to Understand the Heat Stress Response: The Development of Scalable Tools and Methods to Drive Hypothesis Generation [D] . Hubbard, Allen Henry, Jr. 2018

机译：了解热应力响应的数据和 - 致动力驱动方法：开发可扩展工具和方法以推动假设产生
6. Personalized Oncology Suite: integrating next-generation sequencing data and whole-slide bioimages [O] . Andreas Dander, Matthias Baldauf, Michael Sperk, 2014

机译：个性化肿瘤套件：整合下一代测序数据和全幻灯片生物图像
7. Oncology In Vivo Data Integration for Hypothesis Generation [O] . Wei Jia, Chen Ming 2012

机译：体内肿瘤数据集成以生成假设

Oncology in Vivo Data Integration for Hypothesis Generation

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