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MECHANICS OF PLASMA MEMBRANE VESICLES IN CELLS

机译:细胞中血浆膜囊泡的力学

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摘要

In this study, mechanics of plasma membrane vesicles in cells have been theoretically investigated based on minimization of bending and in-plane shear strain energy of the membrane. The results are: ⅰ) The vesicles change their shapes dramatically as the opening radius increases. During the large deformation process, the sudden shape changes due to spontaneous curvature were observed accompanying with a step-like increase in strain energy, ⅱ) Effects of the in-plane shear modulus μ upon the equilibrium shape of the connected system were observed particularly in the vicinity of the neck part and the constricted part of the vesicles where curvature changes dramatically, ⅲ) The computed shape given by the present method is relatively in good agreement with the results observed on electron micrographs.
机译:在这项研究中,基于最小化膜的弯曲和面内剪切应变能,从理论上研究了细胞质膜囊泡的力学。结果是:ⅰ)囊泡的形状随着开口半径的增加而急剧变化。在大变形过程中,观察到由于自发曲率引起的突然形状变化,同时应变能呈阶梯状增加。ⅱ)观察到面内剪切模量μ对连接系统平衡形状的影响,特别是在在曲率急剧变化的囊泡的颈部和颈缩部分附近,ⅲ)通过本方法给出的计算形状与在电子显微照片上观察到的结果相对较好。

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