首页> 外文会议>Lasers in Dentistry XIII; Progress in Biomedical Optics and Imaging; vol.8 no.2; Proceedings of SPIE-The International Society for Optical Engineering; vol.6425 >A new multi-wavelength optical-plethysmograph for quantitative determination of pulpal hemoglobin content and oxygen level using green and near-infrared LEDs
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A new multi-wavelength optical-plethysmograph for quantitative determination of pulpal hemoglobin content and oxygen level using green and near-infrared LEDs

机译:一种新型的多波长光学体积描记仪,使用绿色和近红外LED定量测定牙髓血红蛋白含量和氧含量

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A new multi-wavelength optical-plethysmograph has been designed to study the relation between the transmitted optical density (OD) of the tooth vs. hemoglobin (Hb) content and oxygen saturation (SO_2) of the pulpal blood using the 467, 506, 522 and 810 nm light emitting diodes (LEDs). The experimental model utilized the extracted human upper incisor where the pulp cavity was filled with the blood having various values of Hb and SO_2. A resin cap was made to fit the tooth crown and optical fibers for transmission measurement. The LEDs were pulsed sequentially at 520 Hz with the pulse duration of 240 μs. The OD as a function of Hb for the isosbestic wavelengths of 506 and 522 nm increased almost linearly from 8.0 to 11.0 for Hb changing from 0.0 (saline control) to 2.5 g/dL, but beyond 2.5 g/dL no change was observed. At 810 nm, the OD increased linearly till Hb of 13.4 g/dL, but its change was much smaller with 1.0 OD per 13.4 g/dL. As for SO_2, the OD at 467 nm with Hb of 1.0 g/dL that simulated the mean pulpal Hb content in vivo varied by about 1.0 for SO_2 changing from 100 to 40 %. The OD change with respect to Hb change at 506 and 522 nm showed better sensitivity than that at 810 nm. The combination of 467 and 506 or 522 nm wavelengths can provide a noninvasive measurement of both pulpal Hb content and SO_2 to diagnose pulp vitality of teeth in vivo.
机译:设计了一种新的多波长光学体积描记器,使用467、506、522研究牙的透射光密度(OD)与血红蛋白(Hb)含量和牙髓血氧饱和度(SO_2)之间的关系。和810 nm发光二极管(LED)。实验模型利用提取的人类上切牙,其中牙髓腔中充满了具有各种Hb和SO_2值的血液。制成树脂盖以适合牙冠和光纤以进行透射测量。将LED依次以520 Hz的脉冲持续时间为240μs脉冲。对于506和522 nm等吸收波长,OD随Hb的变化几乎线性地从8.0增加到11.0,Hb从0.0(盐水对照)变为2.5 g / dL,但超过2.5 g / dL则未观察到变化。在810 nm处,OD线性增加直至Hb为13.4 g / dL,但其变化很小,每13.4 g / dL为1.0 OD。至于SO_2,模拟SO_2在体内平均纸浆Hb含量的Hb为1.0 g / dL,在467 nm处的OD值变化约1.0,SO_2从100%变为40%。相对于Hb在506和522 nm处的OD变化显示出比810 nm处更高的灵敏度。 467和506或522 nm波长的组合可以提供牙髓Hb含量和SO_2的无创测量,以诊断体内牙髓的活力。

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