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首页> 外文会议>Conference on Lasers in Dentistry >A new multi-wavelength optical-plethysmograph for quantitative determination of pulpal hemoglobin content and oxygen level using green and near-infrared LEDs
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A new multi-wavelength optical-plethysmograph for quantitative determination of pulpal hemoglobin content and oxygen level using green and near-infrared LEDs

机译：一种新的多波长光学体积描谱，用于定量测定使用绿色和近红外LED的扶手血红蛋白含量和氧气水平

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A new multi-wavelength optical-plethysmograph has been designed to study the relation between the transmitted optical density (OD) of the tooth vs. hemoglobin (Hb) content and oxygen saturation (SO_2) of the pulpal blood using the 467, 506, 522 and 810 nm light emitting diodes (LEDs). The experimental model utilized the extracted human upper incisor where the pulp cavity was filled with the blood having various values of Hb and SO_2. A resin cap was made to fit the tooth crown and optical fibers for transmission measurement. The LEDs were pulsed sequentially at 520 Hz with the pulse duration of 240 μs. The OD as a function of Hb for the isosbestic wavelengths of 506 and 522 nm increased almost linearly from 8.0 to 11.0 for Hb changing from 0.0 (saline control) to 2.5 g/dL, but beyond 2.5 g/dL no change was observed. At 810 nm, the OD increased linearly till Hb of 13.4 g/dL, but its change was much smaller with 1.0 OD per 13.4 g/dL. As for SO_2, the OD at 467 nm with Hb of 1.0 g/dL that simulated the mean pulpal Hb content in vivo varied by about 1.0 for SO_2 changing from 100 to 40 %. The OD change with respect to Hb change at 506 and 522 nm showed better sensitivity than that at 810 nm. The combination of 467 and 506 or 522 nm wavelengths can provide a noninvasive measurement of both pulpal Hb content and SO_2 to diagnose pulp vitality of teeth in vivo.
机译：设计了一种新的多波长光学体积素，用于研究使用467,506,522的牙齿血液（HB）血红蛋白（HB）含量和氧饱和度（SO_2）之间的透射光学密度（OD）与靶血红蛋白（HB）含量和氧饱和度（SO_2）之间的关系和810 nm发光二极管（LED）。实验模型利用所提取的人上部门牙，其中纸浆腔填充有具有Hb和SO_2各种值的血液的血液。制备树脂盖以适合齿冠和光纤以进行透射测量。 LED在520Hz中序列地脉冲，脉冲持续时间为240μs。作为506和522nm的Isosbestic波长的Hb的函数的OD几乎线性地从8.0到11.0增加到0.0（盐水管）至2.5g / dL，但超过2.5g / dl未观察到。在810nm处，OD线性增加至13.4g / dl的Hb，但其变化小得多，每13.4g / dl为1.00DD。对于SO_2，467nm的OD，具有1.0g / d1的HB，其模拟体内平均粉浆Hb含量为0.0μm的变化为100％至40％。在506和522nm处相对于Hb变化的OD改变显示比810nm更好的敏感性。 467和506或522nm波长的组合可以提供副HB含量的非侵入性测量，并且SO_2以诊断体内牙齿的牙髓活力。

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