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Continuous imaging of the blood vessels in tumor mouse dorsal skin window chamber model by using SD-OCT

机译:使用SD-OCT对肿瘤小鼠背部皮肤窗腔室模型中的血管进行连续成像

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摘要

Optical Coherence Tomography (OCT) has been widely applied into microstructure imaging of tissues or blood vessels with a series of advantages, including non-destructiveness, real-time imaging, high resolution and high sensitivity. In this study, a Spectral Domain OCT (SD-OCT) system with higher sensitivity and signal-to-noise ratio (SNR) was built up, which was used to observe the blood vessel distribution and blood flow in the dorsal skin window chamber of the nude mouse tumor model. In order to obtain comparable data, the distribution images of blood vessels were collected from the same mouse before and after tumor injection. In conclusion, in vivo blood vessel distribution images of the tumor mouse model have been continuously obtained during around two weeks.
机译:光学相干断层扫描(OCT)已被广泛应用于组织或血管的微结构成像,具有一系列优点,包括无损,实时成像,高分辨率和高灵敏度。本研究建立了具有较高灵敏度和信噪比(SNR)的光谱域OCT(SD-OCT)系统,该系统用于观察大鼠背侧皮肤窗腔中的血管分布和血流裸鼠肿瘤模型。为了获得可比较的数据,在注射肿瘤之前和之后从同一只小鼠收集血管的分布图像。总之,已经在大约两周内连续获得了肿瘤小鼠模型的体内血管分布图像。

著录项

  • 来源
    《》|2016年|96973N.1-96973N.4|共4页
  • 会议地点 San Francisco CA(US)
  • 作者单位

    Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, Guangdong Province, China, 518060;

    Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, Guangdong Province, China, 518060;

    Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, Guangdong Province, China, 518060;

    Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, Guangdong Province, China, 518060;

    Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, Guangdong Province, China, 518060;

    Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, Guangdong Province, China, 518060;

    Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, Guangdong Province, China, 518060;

    Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, Guangdong Province, China, 518060;

    Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, Guangdong Province, China, 518060;

    Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, Guangdong Province, China, 518060;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Optical Coherence Tomography (OCT); Dorsal Skin Window Chamber; Blood vessel Distribution;

    机译:光学相干断层扫描(OCT);背侧皮肤窗室;血管分布;

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