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Clinical experience with CT colonography

机译:CT结肠术的临床经验

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摘要

Since the introduction of Computed Tomographic Colonography (CTC) in 1995, many advances in computer equipment and software have become available. Despite these advances, the promise of colon cancer prevention has not been realized. A colorectal screening tool that performs at a high level, is acceptable to patients, and can be performed safely and at low cost holds promise of saving lives in the future. Our institution has performed over two hundred seventy five clinical CTC examinations. These scans, which each entail a supine and a prone acquisition, only differ from our research protocol in the necessity of an expeditious interpretation. Patients arrive for their CTC examination early in the morning following a period of fasting and bowel preparation. If a CTC examination has a positive finding, the patient is scheduled for colonoscopic polypectomy that same morning. To facilitate this, the patients are required to continue fasting until the CTC examination has been interpreted. It is therefore necessary to process the CTC examination very quickly to minimize patient discomfort. A positive CTC result occurred in fifteen percent of examinations. Among these positive results, the specificity has been in excess of ninety five percent. Additionally, life threatening extra-colonic lesions were discovered in two percent of the screened population.
机译:自1995年引入计算机断层扫描结肠造影(CTC)以来,计算机设备和软件的许多进展都已可用。尽管有这些进步,但尚未实现结肠癌预防的承诺。患者可接受在高水平下进行的结直肠筛查工具,并且可以安全地进行,并且在未来的储蓄生命中可以安全地进行。我们的机构已经超过了两百七十五个临床CTC检查。这些扫描每次都需要仰卧和易受收购,只有我们的研究方案的必要性迅速解释。患者在禁食和肠道准备期间清早到达CTC考试。如果CTC检查具有阳性发现,则会调度患者同期的结肠镜综合切除术。为了促进这一点,患者需要继续禁食,直到CTC检查被解释。因此,有必要非常快速地处理CTC检查,以最大限度地减少患者的不适。阳性CTC结果以15%的考试发生。在这些阳性结果中,特异性超过百分之九十五。此外,威胁危及结肠病变的终身均为筛选人群的百分之次。

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