GROWTH, SUBSTRATE CONSUMPTION AND PRODUCT FORMATION IN BATCH, CONTINUOUS AND FED-BATCH CULTURES OF Escherichia coli W3110(pEC901)

机译：大肠杆菌W3110（pEC901）的分批，连续和分批培养中的生长，基质消耗和产物形成

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Acetic acid is produced when Escherichia coli W3110 (pEC901) is cultivated in medium containing glucose. Acetic acid formation and its effects on cell growth and interferon production were investigated by using shake-flask and chemostat cultures. Acetic acid greatly inhibited cell growth and interferon production, when it was removed from the culture, cellular interferon content increased by more than threefold.

机译：在含葡萄糖的培养基中培养大肠杆菌W3110（pEC901）会产生乙酸。通过使用摇瓶和化学恒温培养来研究乙酸的形成及其对细胞生长和干扰素产生的影响。乙酸极大地抑制了细胞的生长和干扰素的产生，将其从培养物中去除后，细胞中干扰素的含量增加了三倍以上。

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《1996 Asian-Pacific chemical reaction engineering forum(APCRE'96)》|1996年|52-57|共6页
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Qin Ye; Juntang Yu; Xia Zhao;
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正文语种
中图分类化学反应过程;
关键词
interferon αA; acetic acid; escherichia coli W3110 (pEC901);

机译：干扰素αA;醋酸;大肠杆菌W3110（pEC901）;

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专利

1. The use of multi-parameter flow cytometry to compare the physiologicalresponse of Escherichia coli W3110 to glucose limitation during batch,fed-batch and continuous culture cultivations [J] . Hewitt CJ., Caron GNV., Nienow AW., Journal of Biotechnology . 1999,第2a3期

机译：使用多参数流式细胞术比较大肠杆菌W3110在分批，喂料分批和连续培养过程中对葡萄糖限制的生理反应
2. Improved productivity of poly (4-hydroxybutyrate) (P4HB) in recombinant Escherichia coli using glycerol as the growth substrate with fed-batch culture [J] . Sylvaine Le Meur, Manfred Zinn, Thomas Egli, Microbial Cell Factories . 2014,第1期

机译：使用甘油作为分批分批培养的生长底物，提高了重组大肠杆菌中聚（4-羟基丁酸酯）（P4HB）的生产率
3. Utility of an Escherichia coli strain engineered in the substrate uptake system for improved culture performance at high glucose and cell concentrations: An fed-batch cultures [J] . Lara AR, Caspeta L, Gosset G, Biotechnology and Bioengineering . 2008,第4期

机译：在底物摄取系统中工程化的大肠杆菌菌株在高葡萄糖和细胞浓度下可提高培养性能的实用性：分批补料培养
4. GROWTH, SUBSTRATE CONSUMPTION AND PRODUCT FORMATION IN BATCH, CONTINUOUS AND FED-BATCH CULTURES OF ESCHERICHIA COLI W3110(pEC901) [C] . Qin Ye, Juntang Yu, Xia Zhao 1996 Asian-Pacific chemical reaction engineering forum(APCRE'96) . 1996

机译：大肠埃希氏菌W3110（pEC901）的分批，连续和分批培养的生长，基质消耗和产品形成
5. Growth kinetics of Bacillus thuringiensis batch, fed-batch and continuous bioreactor cultures. [D] . Rivera, David. 1999

机译：苏云金芽孢杆菌分批，补料分批和连续生物反应器培养的生长动力学。
6. Improved productivity of poly (4-hydroxybutyrate) (P4HB) in recombinant Escherichia coli using glycerol as the growth substrate with fed-batch culture [O] . Sylvaine Le Meur, Manfred Zinn, Thomas Egli, 2014

机译：使用甘油作为分批分批培养的生长底物提高了重组大肠杆菌中聚（4-羟基丁酸酯）（P4HB）的生产率
7. Enhanced growth and recombinant protein production of Escherichia coli by a perfluorinated oxygen carrier in miniaturized fed-batch cultures [O] . Pilarek Maciej, Glazyrina Julia, Neubauer Peter 2011

机译：小型补料分批培养中全氟氧载体增强大肠杆菌的生长和重组蛋白生产

GROWTH, SUBSTRATE CONSUMPTION AND PRODUCT FORMATION IN BATCH, CONTINUOUS AND FED-BATCH CULTURES OF Escherichia coli W3110(pEC901)

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