EFFECT OF SUPEROXIDE DISMUTASE DERIVATIVES ON REACTIVE OXYGEN SPECIES-RELATED IMPAIRMENT OF ALVEOLAR EPITHELIAL CELLS

机译：超氧化物歧化酶衍生物对肺泡上皮细胞活性氧相关损伤的影响

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Therapeutic potentials of superoxide dismutase (SOD) derivatives against reactive oxygen species-related lung injury were evaluated in primary cultured rabbit alveolar epithelial cells. Cationized SOD exhibited much greater effect than native SOD and Man-SOD. It is due to increased uptake of SOD into the cell interior by cationization.

机译：在原代培养的兔肺泡上皮细胞中评估了超氧化物歧化酶（SOD）衍生物对与活性氧相关的肺损伤的治疗潜力。阳离子化的SOD表现出比天然SOD和Man-SOD更大的效果。这是由于阳离子化增加了SOD向细胞内部的吸收。

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《Proceedings of the 29th Annual Meeting of the Controlled Release Society》|2002年|p.1010-1011|共2页
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N. Ishimoto; K. Nagayoshi; M. Nishikawa; F. Yamashita; M. Hashida;
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中图分类化学工业;
关键词
ROS-related injury; SOD; cationized SOD; alveolar epithelial cells;

机译：ROS相关损伤; SOD;阳离子化SOD;肺泡上皮细胞;

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专利

1. Transgenic extracellular superoxide dismutase protects postnatal alveolar epithelial proliferation and development during hyperoxia. [J] . Auten RL, OReilly MA, Oury TD, American Journal of Physiology . 2006,第1期

机译：转基因细胞外超氧化物歧化酶在高氧期间保护产后肺泡上皮的增殖和发育。
2. A correlation of reactive oxygen species accumulation by depletion of superoxide dismutases with age-dependent impairment in the nervous system and muscles of Drosophila adults [J] . Oka Saori, Hirai Jun, Yasukawa Takashi, Biogerontology . 2015,第4期

机译：果蝇成人神经系统和肌肉中超氧化物歧化酶耗竭引起的活性氧累积与年龄相关损伤的相关性
3. oiwa, a female gametophytic mutant impaired in a mitochondrial manganese-superoxide dismutase, reveals crucial roles for reactive oxygen species during embryo sac development and fertilization in Arabidopsis. [J] . Martin M. V., Fiol D. F., Sundaresan V., The Plant Cell . 2013,第5期

机译：oiwa是线粒体锰超氧化物歧化酶受损的雌配子体突变体，在拟南芥的胚囊发育和受精过程中揭示了活性氧的关键作用。
4. EFFECT OF SUPEROXIDE DISMUTASE DERIVATIVES ON REACTIVE OXYGEN SPECIES-RELATED IMPAIRMENT OF ALVEOLAR EPITHELIAL CELLS [C] . N. Ishimoto, K. Nagayoshi, M. Nishikawa, Annual meeting of the Controlled Release Society . 2002

机译：超氧化物歧化酶衍生物对肺泡上皮细胞活性氧物质的影响
5. Transgenic analysis of manganese superoxide dismutase and reactive oxygen metabolism in Drosophila melanogaster. [D] . Atoum, Manar Fayiz. 1997

机译：果蝇中锰超氧化物歧化酶和活性氧代谢的转基因分析。
6. oiwa a Female Gametophytic Mutant Impaired in a Mitochondrial Manganese-Superoxide Dismutase Reveals Crucial Roles for Reactive Oxygen Species during Embryo Sac Development and Fertilization in Arabidopsis [O] . María Victoria Martin, Diego Fernando Fiol, Venkatesan Sundaresan, 2013

机译：oiwa一种线粒体锰超氧化物歧化酶受损的女性配子体突变体在拟南芥胚囊发育和受精过程中揭示了活性氧物种的关键作用
7. Activation of Matrix Metalloproteinase-2 by Overexpression of Manganese Superoxide Dismutase in Human Breast Cancer MCF-7 Cells Involves Reactive Oxygen Species* [O] . 2015

机译：过量表达锰超氧化物歧化酶在人乳腺癌mCF-7细胞中激活基质金属蛋白酶-2涉及活性氧物种*

EFFECT OF SUPEROXIDE DISMUTASE DERIVATIVES ON REACTIVE OXYGEN SPECIES-RELATED IMPAIRMENT OF ALVEOLAR EPITHELIAL CELLS

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