Antibody immobilization within glass microstructured fibers: a route to sensitive and selective biosensors

机译：将抗体固定在玻璃微结构纤维中：通往灵敏和选择性生物传感器的途径

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Glass microstructured optical fibers have been rendered biologically active for the first time active via the immobilization of antibodies within the holes in the fiber cross-section. This has been done by introducing coating layers to the internal surfaces of soft glass fibers. The detection of proteins that bind to these antibodies has been demonstrated experimentally within this system via the use of fluorescence labeling. The approach combines the sensitivity resulting from the long interaction lengths of filled fibers with the selectivity provided by the use of antibodies.

机译：通过将抗体固定在纤维横截面上的孔内，玻璃微结构化的光纤首次具有生物活性。这是通过在软玻璃纤维的内表面引入涂层来完成的。通过使用荧光标记，已在该系统内通过实验证明了与这些抗体结合的蛋白质的检测。该方法将填充纤维的长相互作用长度所产生的灵敏度与使用抗体所提供的选择性相结合。

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《International Conference on Optical Fibre Sensors》|2008年|223-224|共4页
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作者
T.M. Monro; Y. Ruan; H. Ebendorff-Heidepriem; H. Foo; P. Hoffmann; R.C. Moore;
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中图分类光波通信、激光通信;
关键词
fiber fabrication processing; fluorescence; sensing; biosensing; protein sensing;

机译：纤维制造与加工;荧光;传感;生物传感;蛋白质传感;

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4. Antibody immobilization within glass microstructured fibers: a route to sensitive and selective biosensors [C] . T.M. Monro, Y. Ruan, H. Ebendorff-Heidepriem, International Conference on Optical Fiber Sensors . 2008

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Antibody immobilization within glass microstructured fibers: a route to sensitive and selective biosensors

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