Enhanced Gene Expression in Coxsackie-Adenovirus Receptor Deficient Cells by Anionic LiposomeEncapsulated Adenovirus

机译：阴离子脂质体包封的腺病毒增强柯萨奇-腺病毒受体缺陷细胞中的基因表达

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Adenovectors were encapsulated into anionicliposomes by calcium-induced phase changesmethod to enhance their transduction efficiency incoxsackie-adenovirus receptor deficient cells and toprotect them from neutralizing antibodies. Thisdelivery strategy is useful for applications usingadenovectors, in which the target cells lackadenoviral receptors or in which the recipient has aneutralizing antibody response.

机译：腺载体被封装到阴离子载体中钙诱导的相变导致脂质体增强其转导效率的方法柯萨奇-腺病毒受体缺陷细胞和保护它们免受中和抗体的侵害。这交付策略对于使用以下内容的应用程序很有用靶细胞缺乏的腺载体腺病毒受体或受体具有中和抗体反应。

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《Annual meeting exposition of the Controlled Release Society》|2009年|p.1-2|共2页
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Zhirong Zhong; Zhirong Zhang; Xun Sun;
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中图分类药学;诊断学;
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专利

1. Anionic liposomes increase the efficiency of adenovirus-mediated gene transfer to Coxsackie-adenovirus receptor deficient cells [J] . ZhongZ., ShiS., HanJ., Molecular pharmaceutics . 2010,第1期

机译：阴离子脂质体可提高腺病毒介导的基因转移至柯萨奇腺病毒受体缺陷细胞的效率
2. Late resistance to adenoviral p53-mediated apoptosis caused by decreased expression of Coxsackie-adenovirus receptors in human lung cancer cells. [J] . Tango Y, Taki M, Shirakiya Y, Cancer science. . 2004,第5期

机译：对人肺癌细胞中柯萨奇腺病毒受体表达降低引起的对腺病毒p53介导的凋亡的晚期耐药性。
3. Lineage differentiation-associated loss of adenoviral susceptibility and Coxsackie-adenovirus receptor expression in human mesenchymal stem cells. [J] . Hung SC, Lu CY, Shyue SK, Stem Cells . 2004,第7期

机译：人间充质干细胞中谱系分化相关的腺病毒敏感性和柯萨奇腺病毒受体表达的丧失。
4. Enhanced Gene Expression in Coxsackie-Adenovirus Receptor Deficient Cells by Anionic Liposome Encapsulated Adenovirus [C] . Annual meeting exposition of the Controlled Release Society . 2009

机译：阴离子脂质体包封腺病毒Coxsackie-adenovirus受体缺陷细胞中增强基因表达
5. Efficient adenovirus-mediated transgene expression in human acute myeloid leukemia cells: The roles of the integrins alphavbeta5, alphavbeta3, and of the coxsackievirus and adenovirus receptor [D] . Aswald, Sandra. 2002

机译：在人类急性髓样白血病细胞中高效腺病毒介导的转基因表达：整合素αvbeta5，αvbeta3以及柯萨奇病毒和腺病毒受体的作用
6. Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes. [O] . E Wagner, K Zatloukal, M Cotten, 1992

机译：腺病毒与转铁蛋白-聚赖氨酸/ DNA复合物的偶联极大地增强了受体介导的基因传递和转染基因的表达。
7. Late resistance to adenoviral p53-mediated apoptosis caused by decreased expression of Coxsackie-adenovirus receptors in human lung cancer cells [O] . Yasuhisa Tango, Masaki Taki, Yoshiko Shirakiya, 2004

机译：通过人肺癌细胞中Coxsackie-Adenovirus受体表达降低引起的腺病毒P53介导的细胞凋亡

Enhanced Gene Expression in Coxsackie-Adenovirus Receptor Deficient Cells by Anionic LiposomeEncapsulated Adenovirus

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