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首页> 外文会议>International conference on environmental biotechnology and materials engineering;EBME 2011 >Prediction of Antigenic Epitopes for Coat Protein of Potato virus Y
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Prediction of Antigenic Epitopes for Coat Protein of Potato virus Y

机译：马铃薯Y病毒外壳蛋白抗原表位的预测

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Potato virus Y(PVY) is one of the most important viruses that infect Solanaceous crops. In the study, the antigenic epitopes were predicted using computer-assisted analysis, and many potential regions of antigenic epitopes were located. Many properties of coat protein, such as the antigenic index, a-helix, β-sheet, β-turn, coil structure, hydrophilicity, surface probability, and flexibility, were analyzed with several algorithms in some softwares. Based on the rules for location the antigenic epitopes in the regions including β-turns and coil structures with the high hydrophilicity and surface probability, the predicted epitopes were located in the region of amino acid position 8-22, 24-38, 45-55, 240-255, respectively. It is helpful to prepare the antiserum of PVY based on the prediction result of antigenic epitope.
机译：马铃薯Y（PVY）病毒是感染茄类作物的最重要病毒之一。在这项研究中，使用计算机辅助分析预测了抗原表位，并找到了抗原表位的许多潜在区域。在某些软件中使用几种算法分析了外壳蛋白的许多特性，例如抗原指数，α-螺旋，β-折叠，β-转角，螺旋结构，亲水性，表面概率和柔韧性。根据抗原表位在具有高亲水性和表面概率的β-转角和卷曲结构区域中的定位规则，预测的表位位于氨基酸位置8-22、24-38、45-55的区域，分别为240-255。根据抗原表位的预测结果，制备PVY抗血清是有帮助的。

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