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首页> 外文会议>International conference on biotechnology, chemical and materials engineering >Evaluation of the anti-inflammatory and analgesic activities of the total saponins extracted from fermented Polygala japonica HOUTT
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Evaluation of the anti-inflammatory and analgesic activities of the total saponins extracted from fermented Polygala japonica HOUTT

机译：评价来自发酵聚集粳稻Houtt的抗炎和镇痛活性的抗炎和镇痛活性

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This study was to investigate the anti-inflammatory and analgesic activities of the total saponins extracted from fermented Polygala japonica Houtt (FPH) compared with that of unfermented Polygalajaponica Houtt (UFPH).The total saponins extracted from FPH and UFPH were evaluated for anti-inflammatory activity in xylene-induced ear swelling and acetic acid-induced vascular permeability models in mice,analgesic activity in acetic acid-induced writhing and hot plate models in mice.The total saponins extracted from FPH had the significant anti-inflammatory (p＜0.001) and analgesic (p＜0.01) activities with the doses of 6 g/kg b.w.in mice.The results of this experimental study thus strongly support the potential significant use of the total saponins extracted from FPH for pain and inflammatory.
机译：该研究是研究从发酵的聚集粳稻Houtt（FPH）中提取的总皂苷的抗炎和镇痛活性与未加入的Polygalajaponica Houtt（UFPH）。评价来自FPH和UFPH中提取的总皂苷进行抗炎二甲苯诱导的耳肿胀和乙酸诱导的小鼠血管渗透性模型的活性，乙酸诱导的替代卷曲和小鼠的热板模型中的镇痛活性。从FPH中提取的总皂苷具有显着的抗炎（P <0.001）镇痛（P <0.01）活性为6g / kg Bwin小鼠的剂量。因此，该实验研究的结果强烈支持从FPH中提取的总皂苷的潜在大量使用疼痛和炎症。

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