Total internal reflection ellipsometry in the investigation of phenomena at surfaces and interfaces for biosensing

机译：全内反射椭圆仪用于研究生物传感表面和界面处的现象

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Ellipsometry, particularly spectroscopic ellipsometry, is a very sensitive, nondestructive experimental technique of thin film characterisation. The recently proposed method of Total internal reflection ellipsometry (TIRE) combines the advantages of spectroscopic ellipsometry and the Kretschmann type SPR geometry of total internal reflection. The modeling reveals detection limit of changes in the bulk refractive index, Δn= 1.5×10 which represents the instrumental potential for detecting an analyte at several pmol/liter in a solution. These results were proven by experimental studies on monitoring changes in adsorbed layers (at the metal / dielectric interface) caused by specific binding of biomolecules from the surrounding solution.

机译：椭圆偏振法，特别是光谱椭圆偏振法，是一种非常灵敏，无损的薄膜表征实验技术。最近提出的全内反射椭圆仪（TIRE）方法结合了光谱椭圆仪的优点和全内反射的Kretschmann型SPR几何形状。该模型揭示了总折射率变化的检测极限，Δn= 1.5×10，代表了检测溶液中数pmol / l的分析物的仪器潜力。这些结果已通过实验研究证明，该研究监测了生物分子与周围溶液的特异性结合所引起的吸附层（在金属/介电界面处）的变化。

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《International Conference on Advanced Semiconductor Devices and Microsystems》|2014年|1-4|共4页
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Chlpik J.; Bombarova K.; Cirak J.;
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bio-optics; biosensors; ellipsometry; Kretschmann type SPR geometry; biosensing; bulk refractive index; interface phenomena; nondestructive experimental technique; spectroscopic ellipsometry; surface phenomena; thin film characterisation; total internal reflection ellipsometry; Ellipsometry; Metals; Optical surface waves; Plasmons; Reflection; Surface waves; Tires;

机译：生物光学;生物传感器;椭圆光度法; Kretschmann型SPR几何;生物传感;体折射率;界面现象;无损实验技术;光谱椭圆光度法;表面现象;薄膜特性;全内反射椭圆光度法;椭圆率法;金属;光学表面波;等离子;反射;表面波;轮胎;

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1. Total internal reflection ellipsometry: ultrahigh sensitivity for protein adsorption on metal surfaces [J] . Michal Poksinski, Hans Arwin Optics Letters . 2007,第10期

机译：全内反射椭圆光度法：对蛋白质在金属表面的吸附具有超高灵敏度
2. In situ monitoring of metal surfaces exposed to milk using total internal reflection ellipsometry [J] . Michal Poksinski, Hans Arwin Sensors and Actuators. B, Chemical . 2003,第3期

机译：使用全内反射椭圆仪现场监测暴露于牛奶的金属表面
3. Treatment of Surface Plasmon Resonance (SPR) Background in Total Internal Reflection Ellipsometry: Characterization of RNA Polymerase II Film Formation [J] . Du?an Hemzal, Yu Ri Kang, Jan Dvo?ák, Applied Spectroscopy: Society for Applied Spectroscopy . 2019,第3期

机译：总内反射椭圆形测定法中表面等离子体共振（SPR）背景的处理：RNA聚合酶II膜形成的表征
4. Total internal reflection ellipsometry in the investigation of phenomena at surfaces and interfaces for biosensing [C] . Chlpik J., Bombarova K., Cirak J. International Conference on Advanced Semiconductor Devices and Microsystems . 2014

机译：在生物传感的表面和界面处的现象调查中的全内反射椭圆形
5. Applications of total internal reflection fluorescence microscopic technique for studies of chemical phenomena at the substrate-liquid interface. [D] . Phimphivong, Samrane K. 2008

机译：全内反射荧光显微镜技术在底物-液体界面化学现象研究中的应用。
6. Optical Properties of Thin Films on Transparent Surfaces by Ellipsometry; Internal Reflection for Film Covered Surfaces Near the Critical Angle [O] . Elio Passaglia, Robert R. Stromberg 1964

机译：椭圆偏振法在透明表面上薄膜的光学性质;接近临界角的覆膜表面的内部反射
7. Total internal reflection ellipsometry as a label-free assessment method for optimization of the reactive surface of bioassay devices based on a functionalized cycloolefin polymer [O] . Nam Cao Hoai Le, Vladimir Gubala, Ram P. Gandhiraman, 2010

机译：总内部反射椭圆测定法作为无标记的评估方法，用于基于官能化的环烯聚合物优化生物测定装置的反应性表面
8. An Investigation of the Techniques of Ellipsometry, Internal Reflection Spectroscopy, and Moment Analysis to the Study of Films and Substrates [R] . Palmer, K. F., Williams, M. Z. 1981

机译：椭圆光度法，内反射光谱法和膜片分析法研究薄膜和基材的研究

Total internal reflection ellipsometry in the investigation of phenomena at surfaces and interfaces for biosensing

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