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首页> 外文会议>Annual conference of the International Society of Exposure Science >Data for Policy - Human biomonitoring's contribution to evidence-informed environmental health policy-making
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Data for Policy - Human biomonitoring's contribution to evidence-informed environmental health policy-making

机译：政策数据 - 人类生物监测对证据知识环境健康政策的贡献

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Human Biomonitoring (HBM) data reflect the total amount of a chemical transferred into the human body. Therefore, HBM provides key information for environmental-health policy-makers. Current results of the German HBM system - German Environmental Survey (GerES) and Environmental Specimen Bank (ESB) - highlight important aspects of further strengthening HBM as tool for evidence-informed policy-making: a) Following up trends - HBM can yield early warnings or demonstrate the success of regulation: German ESB data reveal an increase in glyphosate exposure (fraction of 24 h-urine levels ≥ LOQ increased from 10% in 2001 to 40% in 2015). In contrast, Pentachlorophenol - banned as pesticide in Germany in 1989 - decreased in blood plasma from 21 μg/L in 1987 to 0.5 μg/L in 2010 (geometric means), b) Combining HBM with questionnaire and other monitoring data - elucidate routes of exposure: GerES 2003-2006 revealed that cotinine in 3-14 years-old children's morning urine is associated with maternal and paternal self-reported smoking. In the same study, uranium in urine was correlated with uranium in drinking water. No significant associations were found for other metals like nickel or cadmium, c) Evaluating the health-relevance of HBM results - assessment values as a vital tool: HBM values for 19 compounds, derived by the German HBM Commission, are presently available. More than 90% of the ESB samples collected in 2010 and analyzed for PFOA exceeded the HBM-I value. This indicates that health effects cannot be ruled out with sufficient certainty and warrants increased attention in policy-making. The German Environment Agency (UBA) contributes its long-standing experience in transferring HBM data into policy to the European Joint Programme HBM4EU. As one main goal, this initiative makes the appropriate HBM data and complementary information available to policy-makers thus supporting targeted regulatory action in environmental health across Europe.
机译：人生物监测（HBM）数据反映了转移到人体中的化学物质的总量。因此，HBM为环境保健政策制定者提供关键信息。德国HBM系统的当前结果 - 德国环境调查（GERES）和环境标本银行（ESB） - 突出进一步加强HBM作为证据通知政策制定工具的重要方面：a）继趋势 - HBM可以产生早期警告或证明规定的成功：德国ESB数据揭示草甘膦暴露的增加（24 H-尿液水平≥10升至2001年的10％至40％）。相比之下，五氯苯酚 - 1989年禁止德国的农药 - 2010年1987年的21μg/ L的血浆减少到0.5μg/ L（几何手段），b）与问卷调查和其他监测数据相结合的HBM - 阐明暴露：GERES 2003-2006显示，3-14岁儿童早晨尿液中的胞苷与母亲和父亲自我报告的吸烟有关。在同一研究中，尿液中的铀与饮用水中的铀相关。没有针对镍或镉等其他金属发现重大关联，C）评估HBM结果的健康相关性 - 评估值作为重要工具：目前可获得由德国HBM委员会衍生的19种化合物的HBM值。超过90％的2010年收集的ESB样品并分析PFOA超过了HBM-I值。这表明，无法通过足够的确定性排除健康效果，并认证在政策制定中提高关注。德国环境署（UBA）有助于转让HBM数据转移到欧洲联合计划HBM4EU的政策方面的长期经验。作为一个主要目标，这项举措是对政策制定者提供适当的HBM数据和补充信息，从而支持欧洲环境健康的有针对性的监管行动。

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