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首页> 外文会议>Annual conference of the International Society of Exposure Science >Data for Policy - Human biomonitoring's contribution to evidence-informed environmental health policy-making
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Data for Policy - Human biomonitoring's contribution to evidence-informed environmental health policy-making

机译：政策数据-人体生物监测对以证据为依据的环境卫生政策制定的贡献

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Human Biomonitoring (HBM) data reflect the total amount of a chemical transferred into the human body. Therefore, HBM provides key information for environmental-health policy-makers. Current results of the German HBM system - German Environmental Survey (GerES) and Environmental Specimen Bank (ESB) - highlight important aspects of further strengthening HBM as tool for evidence-informed policy-making: a) Following up trends - HBM can yield early warnings or demonstrate the success of regulation: German ESB data reveal an increase in glyphosate exposure (fraction of 24 h-urine levels ≥ LOQ increased from 10% in 2001 to 40% in 2015). In contrast, Pentachlorophenol - banned as pesticide in Germany in 1989 - decreased in blood plasma from 21 μg/L in 1987 to 0.5 μg/L in 2010 (geometric means), b) Combining HBM with questionnaire and other monitoring data - elucidate routes of exposure: GerES 2003-2006 revealed that cotinine in 3-14 years-old children's morning urine is associated with maternal and paternal self-reported smoking. In the same study, uranium in urine was correlated with uranium in drinking water. No significant associations were found for other metals like nickel or cadmium, c) Evaluating the health-relevance of HBM results - assessment values as a vital tool: HBM values for 19 compounds, derived by the German HBM Commission, are presently available. More than 90% of the ESB samples collected in 2010 and analyzed for PFOA exceeded the HBM-I value. This indicates that health effects cannot be ruled out with sufficient certainty and warrants increased attention in policy-making. The German Environment Agency (UBA) contributes its long-standing experience in transferring HBM data into policy to the European Joint Programme HBM4EU. As one main goal, this initiative makes the appropriate HBM data and complementary information available to policy-makers thus supporting targeted regulatory action in environmental health across Europe.
机译：人体生物监测（HBM）数据反映了转移到人体中的化学物质的总量。因此，HBM为环境健康政策制定者提供关键信息。德国HBM系统的最新结果-德国环境调查局（GerES）和环境标本银行（ESB）-强调了进一步加强HBM作为循证决策的工具的重要方面：a）跟进趋势-HBM可以发出预警或证明监管成功：德国ESB数据显示草甘膦暴露量增加（24小时尿液含量≥LOQ的比例从2001年的10％增加到2015年的40％）。相比之下，五氯苯酚-1989年在德国被禁止使用农药-血浆中的血浆含量从1987年的21μg/ L下降到2010年的0.5μg/ L（几何平均值），b）将HBM与问卷和其他监测数据结合使用-阐明了接触：GerES 2003-2006揭示了3-14岁儿童早晨尿液中的可替宁与母亲和父亲自我报告的吸烟有关。在同一项研究中，尿液中的铀与饮用水中的铀相关。没有发现与其他金属如镍或镉有显着关联，c）评估HBM结果的健康相关性-评估值是至关重要的工具：德国HBM委员会提供了19种化合物的HBM值。 2010年收集并分析PFOA的ESB样本中，超过90％超过了HBM-1值。这表明不能充分肯定地排除对健康的影响，因此需要在决策中给予更多关注。德国环境局（UBA）将其在将HBM数据转换为政策方面的长期经验贡献给了欧洲联合计划HBM4EU。作为一项主要目标，该计划为决策者提供了适当的HBM数据和补充信息，从而支持了整个欧洲环境健康方面的针对性监管行动。

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