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The effect of solar-geomagnetic activity during and after hospital admission on coronary events within one year in patients with acute coronary syndromes

机译:在急性冠状动脉综合征患者患者中,在急性冠状动脉综合征的一年内和冠状动脉事件中和冠状动脉事件中的效果

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Background and Aims: Some evidence has been reported the deterioration of the cardiovascularsystem during space storms. There is evidence indicating that geomagnetic storms are associated with decreased heart rate variability; elevated blood pressure, blood coagulation and platelent aggregation, increased blood viscosity, and decelerated blood flow. It is plausible that the heliophysical conditions during and after hospital admission may affect the risk of coronary events in patients with acute coronary syndromes (ACS) during one-year period. Methods:We analyzed the data of 1,400 ACS patients who were admitted to the Hospital of Lithuanian University of Health Sciences, and who survived for more than 4 days. We evaluated the associations between geomagnetic storms (GS), solar proton events (SPE), and solar flares (SF) that occurred 0-3 days before and after hospital admission and the risk of cardiovascular death (CAD), non-fatal ACS, and CABG during a period of one year; the evaluation was based on the multivariate logistic model, controlling for clinical data. Results: After adjustment for clinical variables, GS occurring in conjunction with SF on day before admission increased the risk of CAD by over 2.5 times (OR=2.55 95% CI 1.04-6.28). GS occurring two days after SPE on second day of admission increased the risk of CAD and CABG by over 2.5 times (respectively, OR=2.86 95% CI 1.05-7.79 and OR=3.77 95% CI 1.41-10.1). The risk of CABG increased by over 2 times in patients admitted during the day of GS and one day after SPE. The risk of ACS was by over 1.63 times higher for patients admitted one day before or after solar flares (OR=1.63 95% CI 1.04-2.55); the effect of SF was higher in patients with the greatest risk. Conclusions: These findings suggest that the heliophysical conditions before and after hospital admission affect the risk of major adverse cardiovascular events during one-year period.
机译:背景和目标:一些证据报告了空间风暴期间心血管系统的恶化。有证据表明地磁风暴与降低的心率变异有关;血压升高,血液凝固和血压聚集,增加血液粘度和减速血流量。在一年期间,入学期间和患者入学期间和后的冠状动脉综合征(ACS)的冠状动脉事件风险是合理的。方法:我们分析了1,400名ACS患者的数据,该患者被送往立陶宛卫生科学大学,幸存下来超过4天。我们评估了在医院入院前后发生的0-3天发生的地磁风暴(GS),太阳能质子事件(SPE)和太阳耀斑(SF)之间的关联,以及心血管死亡(CAD),非致命AC的风险,和CABG在一年期间;评估基于多变量物流模型,控制临床数据。结果:调整临床变量后,GS在入院前一天与SF结合发生,将CAD的风险增加超过2.5倍(或= 2.55 95%CI 1.04-6.28)。 GS在入院第二天的SPE后发生两天,增加了CAD和CABG的风险超过2.5倍(分别或= 2.86 95%CI 1.05-7.79和或= 3.77 95%CI 1.41-10.1)。在GS和SPE之后的一天,CABG的风险增加了2次。在太阳耀斑之前或之后的患者入院的患者(或= 1.63 95%CI 1.04-2.55),ACS的风险较高超过1.63倍。风险最大的患者的SF对患者的影响更高。结论:这些研究结果表明,医院入院前后的光性物理条件影响了在一年期间影响了主要不良心血管事件的风险。

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