Background. Overweight is a growing problem. It is associated with diseases which are increase during the last decades. As an example both the BMI (Body Mass Index) and the asthma prevalence are increasing. The question is whether a link exists between these changes. Methods. In the frame of a longitudinal repeated cross-sectional epidemiological study 4925 children in total have been medical checked up. A questionnaire was filled out by the parents. Among other things data were gathered concerning anamnesis, physical measurements, and physician diagnosed diseases, like asthma. Describing the overweight in children's age between 6 and 15 years the BMI was divided in percentiles ＜10%, 10 to 25%, 25 to 75%, 75 to 90%, ＞90% respectively ＞97%. The full data set was available for 3946 children (80.1% of all participants). Results. The lifetime prevalence of asthma was 7.1% (age group until 15 years). The BMI was for the overweight group of 6/8/15 years old kids 18.1/20.1/24.5 kg/m~2 and in the adiposity group 20.2/22.4/27.7 kg/m~2 respectively. Frequent air way infections and parental predisposition enhance the risk for asthma (4.1 vs. 10.9%); boys are more affected than girls (8.1 vs. 6.1%). Starting with the 10%-BMI-percentile the asthma prevalence increases using the above mentioned intervals from 3.6% up to 8.3% for children with overweight (＞90%-BMI-percentile). The logistic regression adjusted for relevant confounders (gender, smoking and passive smoking, parental predisposition, cats, duration of breastfeeding, socioeconomic status) confirms the descriptive results. The BMI dependent adjusted Odds Ratio (range) for asthma was 1.6 (95%CI: 1.0-2.7; p=0.048). Conclusions. The results clearly show that within the group of higher BMI more asthma will detected. Contrary to other studies this study may not confirm that the dependence on asthma from the BMI is bimodal since no higher asthma prevalence was observed in the lower BMI classes. Up to now this pilot study does not answer the question about the underlying processes.
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机译：背景。超重是一个日益严重的问题。它与近几十年来不断增加的疾病有关。例如，BMI（身体质量指数）和哮喘患病率都在增加。问题是这些更改之间是否存在链接。方法。在一项纵向重复横断面流行病学研究的框架内，总共对4925名儿童进行了医学检查。父母填写了调查表。除其他事项外，还收集了有关记忆检查，体格测量以及医生诊断的疾病（例如哮喘）的数据。描述BMI的6至15岁儿童的超重百分比分别分别为＜10％，10至25％，25至75％，75至90％，＞ 90％＞ 97％。完整的数据集可用于3946名儿童（占所有参与者的80.1％）。结果。哮喘的终生患病率为7.1％（年龄组直至15岁）。 BMI分别适用于6/8/15岁的超重组18.1 / 20.1 / 24.5 kg / m〜2和肥胖组的20.2 / 22.4 / 27.7 kg / m〜2。频繁的气道感染和父母的易感性增加患哮喘的风险（4.1比10.9％）;男孩比女孩受影响更大（8.1比6.1％）。从上述体重指数的10％开始，哮喘患病率从超重儿童（> 90％BMI的百分比）的3.6％上升到8.3％。对相关混杂因素（性别，吸烟和被动吸烟，父母的性倾向，猫，母乳喂养的持续时间，社会经济状况）进行的逻辑回归调整证实了描述性结果。哮喘的BMI依赖性调整后的赔率（范围）为1.6（95％CI：1.0-2.7; p = 0.048）。结论结果清楚地表明，在BMI较高的人群中，将发现更多的哮喘。与其他研究相反，该研究可能无法确认BMI对哮喘的依赖性是双峰的，因为在较低BMI类别中未观察到较高的哮喘患病率。到目前为止，该初步研究尚未回答有关基本过程的问题。
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