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首页> 外文会议>Annual conference of the International Society of Exposure Science >Slow release pyrethroid-impregnated indoor linings as a new malaria vector control method
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Slow release pyrethroid-impregnated indoor linings as a new malaria vector control method

机译：缓释拟除虫菊酯浸渍的室内衬层作为一种新的疟疾控制方法

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Background: Indoor Residual Spraying (IRS) and Long-Lasting Insecticide-Treated Nets (LLINs) are the most effective malaria vector control methods. The organochloride pesticide, DDT, is still used for IRS and can retain its efficacy for up to twelve months. However, research indicated that harmful levels of DDT residues are present in indoor air for up to three months after spraying. LLINs only provide protection if people sleep under the net. Certain polymers with insecticide embedded in the fibre can be used as slow release carriers for vector control, possibly becoming a long term substitute for IRS. Aims: To assess the efficacy, durability and community acceptability and perceived efficiency of pyrethroid-impregnated linings in community homes in Limpopo province, South Africa, over a six month period. Methods:A field trial is currently taking place in the community village of Tshilivho in Vhembe district, Limpopo. Forty households (20 mud huts and 20 brick houses) are included. Monofilament polyethylene meshing with one of two deltamethrin-, one of two α-cypermethrin concentrations, or no insecticide were attached along the inside wall of one sleeping hut or room per household. Data on acceptability is gathered with questionnaires, and lining samples are tested bi-monthly for efficacy according to WHO recommended bioassays. Results: The linings yielded positive results in initial laboratory bioassays from field samples collected up to date. Test mosquitoes were exposed for 30 minutes to field samples, resulting in 100% knockdown (KD) within this time. Within 24 hours 100% mortality was noted. Preliminary questionnaire data show that the linings are killing mosquitoes on contact and also less biting is reported. Conclusions:Preliminary results indicate that the use of these pyrethroid-impregnated indoor linings is potentially as successful as IRS. This new and potentially safe method might be a more sustainable approach for vector control. Acknowledgements: The study is supported by the University of Pretoria Centre for Sustainable Malaria Control.
机译：背景：室内残留喷雾（IRS）和持久杀虫剂处理过的蚊帐（LLIN）是最有效的疟疾媒介控制方法。有机氯化物农药DDT仍用于IRS，并且可以保持长达12个月的功效。然而，研究表明，喷雾后长达三个月，室内空气中存在有害水平的DDT残留。仅当人们在网络下睡觉时，LLIN才能提供保护。某些在纤维中嵌入了杀虫剂的聚合物可以用作控制载体的缓释载体，有可能成为IRS的长期替代品。目的：在六个月的时间内评估南非林波波省社区房屋中拟除虫菊酯浸渍的衬里的功效，耐久性和社区可接受性以及感知的效率。方法：目前正在林波波省Vhembe区的Tshilivho社区村进行田间试验。其中包括40户家庭（20个泥棚和20座砖房）。每户一个睡觉的小屋或房间的内壁附着有单丝聚乙烯，其与两种溴氰菊酯中的一种，两种α-氯氰菊酯浓度中的一种或没有杀虫剂啮合。通过问卷调查收集可接受性数据，并根据WHO建议的生物测定法每两个月对衬里样品进行功效测试。结果：在最初的实验室生物测定中，该衬里从迄今收集的田间样品中获得了积极的结果。将测试蚊子暴露在野外样品中30分钟，在此时间内产生100％的击倒（KD）。在24小时内，记录了100％的死亡率。初步的问卷调查数据显示，衬里在接触时会杀死蚊子，而且据报道咬人的次数也更少。结论：初步结果表明，这些拟除虫菊酯浸渍的室内衬砌的使用可能与IRS一样成功。这种新的且可能安全的方法可能是矢量控制的更可持续的方法。致谢：该研究得到比勒陀利亚大学可持续疟疾控制中心的支持。

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