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The relationship between traffic noise exposure and ischemic heart disease: a meta-anaiysis

机译：交通噪声暴露与缺血性心脏病之间的关系：荟萃分析

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Introduction Since publication of the World Health Organization's report Burden of disease for environmental noise in 2011, several new studies on traffic noise and ischemic heart disease (IHD) have been published. There is thus a need for a meta-analytic update of risk estimates for these outcomes. Methods We conducted a systematic review and retained published cohort and case-control studies using road, rail or aircraft noise as exposure. Study-specific results were transformed into risk estimates per 10dB using generalised least squares for trend estimation of summarised dose-response data. Subsequently a random effects meta-analysis was conducted. Results We identified 6 studies for IHD incidence and 4 for mortality. Per 10dB increase in noise, the risk estimate was 1.08 (95% CI 1.03-1.13) for IHD incidence (total of 6,000 new cases). The risk estimate for IHD or myocardial infarction mortality accounting for a total of 22,000 deaths was 1.03 (0.99-1.08). Overall risk estimate was 1.04 (1.01-1.08). Conclusion Preliminary results confirm an increase risk in IHD incidence with traffic noise exposure. Future analysis will address type of traffic source and form of the exposure-response curve before the risk estimates will be used in an assessment of the external health costs of traffic in the Swiss population.
机译：引言自从世界卫生组织于2011年发布报告《环境噪声的疾病负担》以来，关于交通噪声和缺血性心脏病（IHD）的几项新研究已经发表。因此，需要对这些结果进行风险估计的荟萃分析更新。方法我们进行了系统的综述，并保留了已发表的队列，病例对照研究，其中使用道路，铁路或飞机噪声作为暴露因素。特定研究的结果使用广义最小二乘法转换为每10dB的风险估计数，以用于汇总剂量反应数据的趋势估计。随后进行了随机效应荟萃分析。结果我们确定了6项IHD发病率研究和4项死亡率研究。噪声每增加10dB，IHD发生的风险估计为1.08（95％CI 1.03-1.13）（总共6,000例新病例）。 IHD或心肌梗死死亡率（总共22,000例死亡）的风险估计为1.03（0.99-1.08）。总体风险估计为1.04（1.01-1.08）。结论初步结果证实，交通噪声暴露会增加IHD发病风险。在将风险估算用于评估瑞士人口中交通的外部健康成本之前，未来的分析将解决交通来源的类型和暴露-响应曲线的形式。

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