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A Multimodal Sensing Device for Fluorescence Imaging and Electrical Potential Measurement of Neural Activities in a Mouse Deep Brain

机译:荧光成像和鼠标深脑中神经活动电势测量的多峰传感装置

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We have developed a multimodal CMOS sensing device to detect fluorescence image and electrical potential for neural activities in a mouse deep brain. The device consists of CMOS image sensor with on-chip electrodes and excitation light sources, all of which are integrated on a polyimide substrate. The novel feature of this device is its embedded on-chip electrodes which are partially transmit incident light so that the whole image can be acquired by the sensor. We have demonstrated the CMOS sensor device successfully operates in hippocampus area of an anesthetized mouse.
机译:我们开发了一种多模式CMOS传感装置,用于检测鼠标深脑中神经活动的荧光图像和电势。该装置由CMOS图像传感器组成,具有片上电极和激发光源,所有这些都集成在聚酰亚胺基板上。该装置的新颖特征是其嵌入式片上电极,其是部分传输入射光,使得整个图像可以由传感器获取。我们已经证明CMOS传感器装置成功地在麻醉鼠标的海马区域运行。

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