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Hardware implementation of a 1D MPI hybrid system for targeted drug delivery

机译：用于目标药物输送的一维MPI混合系统的硬件实现

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摘要

Targeted drug delivery is an efficient technique to optimize the deliver drug molecules to specific tissues in a human body using magnetic nanoparticles (MNPs) as carriers. By combining an electromagnetic actuation (EMA) and a magnetic particle imaging (MPI) systems [1], we can provide a new system, called the Hybrid Action and Imaging System (HAIS). This paper focuses on hardware implementation and simulation of the 1D HAIS which is studied in our previous work [2]. The challenges in this research are the device fabrication and the 1D HAIS experiments. Moreover, the COMSOL Multiphysics software is used for modeling and simulation of the proposed system. The simulation results will be compared with the experimental results. The proposed control system with one axis can be easily extended to 3D for providing simultaneous navigation and tracking of magnetic nanoparticles in compact and efficient ways.
机译：靶向药物输送是一种有效的技术，可以利用磁性纳米颗粒（MNP）作为载体来优化将药物分子输送到人体中特定组织的能力。通过将电磁驱动（EMA）和磁粉成像（MPI）系统结合起来，我们可以提供一种称为混合动作和成像系统（HAIS）的新系统。本文重点研究一维HAIS的硬件实现和仿真，这在我们先前的工作中已进行了研究[2]。这项研究中的挑战是器件制造和一维HAIS实验。此外，COMSOL Multiphysics软件可用于所提出系统的建模和仿真。仿真结果将与实验结果进行比较。所提出的具有一个轴的控制系统可以轻松地扩展到3D，从而以紧凑而有效的方式提供磁性纳米粒子的同时导航和跟踪。

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