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首页> 外文会议>International Conference on Communication Systems and Network Technologies >A Prototype of Ultrasound Forearm Bone Densitometer in Validation with pDXA Bone Densitometer
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A Prototype of Ultrasound Forearm Bone Densitometer in Validation with pDXA Bone Densitometer

机译：用pDXA骨密度仪验证的超声前臂骨密度仪的原型

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'Osteoporosis' is highly prevalent in India and in other parts of the world. The aged population of both sexes is at higher risk for the disorder. In India, the dual energy X-ray absorptiometry (DXA) bone densitometer, which is considered as the 'gold' standard to measure bone mineral density (BMD) at the hip, spine, and forearm is costly and not widely available. On the other hand, ultrasound (US) based bone densitometer is low cost, and is widely available. The accuracy of the device varies widely between the manufactures. The aim of this study was to design and construct a prototype of US forearm bone densitometer to measure BMD with good sensitivity compared to peripheral (p) DXA as standard. The prototype of the device was constructed using a pair of wideband, flat, composite US transducers (diameter=10mm) operating at a central frequency equal to 0.5MHz. The following US parameters were measured accurately at one third length of ulna bone using the digital storage oscilloscope (DSO): i). Ultrasonic transmit time (ΔT, μsec), and ii). Ultrasonic attenuation (ΔV in volt). The device was validated with a bone phantom with the known BMD value supplied by the pDXA manufacturer. A total number of 40 women, and men, aged 30 years and below, as well as aged 45 years and above were studied. In each subject, both forearm BMD (g/cm2) by pDXA and US parameters of the ulna bone by the prototype bone densitometer was measured at standard conditions. All the obtained data were analyzed statistically. It was found that, in total women studied (n=20), the forearm BMD by DXA was correlated statistically significantly with both the measured ΔT and ΔV values by the prototype bone densitometer. On the other hand, in total men studied (n=20), the forearm BMD by pDXA was correlated statistically significantly only with measured ΔT value by the prototype bone densitometer. Also, it was- found that, in old age women group (n=10), the calculated percentage difference in the mean values of US parameters was greater statistically significant than the corresponding BMD value when compared to young women's group (n=10). On the other hand, in old age men group (n=10), the calculated percentage difference in the mean values of both US parameters and BMD value were not statistically significant, when compared to the corresponding values of young women's group (n=10). The prototype device can be useful in the evaluation of the disease with good accuracy.
机译：“骨质疏松症”在印度和世界其他地区非常普遍。两性的老年人口患该病的风险较高。在印度，双能X射线骨密度仪（DXA）骨密度仪被认为是测量臀部，脊柱和前臂的骨矿物质密度（BMD）的“金”标准，价格昂贵，而且尚未广泛使用。另一方面，基于超声（US）的骨密度计价格低廉，并且被广泛使用。在不同的制造商之间，设备的精度差异很大。这项研究的目的是设计和构建美国前臂骨密度仪的原型，与标准的外围（p）DXA相比，它具有良好的灵敏度来测量BMD。该设备的原型是使用一对宽带，扁平，复合美国换能器（直径= 10mm）在中心频率等于0.5MHz的条件下构建的。使用数字存储示波器（DSO）在尺骨长度的三分之一处准确测量了以下US参数：i）。超声波发射时间（ΔT，微秒），和ii）。超声波衰减（伏特的ΔV）。该设备已通过由pDXA制造商提供的已知BMD值的骨模进行了验证。研究对象为40名年龄在30岁以下的男性和45岁以上的男性和女性。在每个受试者中，均在标准条件下测量了通过pDXA测得的前臂BMD（g / cm2）和通过原型骨密度计测得的尺骨的US参数。对所有获得的数据进行统计分析。研究发现，在总共20名女性中，DXA测得的前臂BMD与原型骨密度仪测得的ΔT和ΔV值在统计学上显着相关。另一方面，在总共研究的男性中（n = 20），pDXA测得的前臂BMD仅与原型骨密度仪测得的ΔT值具有统计学显着的相关性。此外，还发现，在老年妇女组（n = 10）中，与年轻妇女组（n = 10）相比，美国参数平均值的计算出的百分比差异在统计学上大于相应的BMD值。 。另一方面，在老年男性组（n = 10）中，与年轻女性组的相应值（n = 10）相比，美国参数和BMD值均值的计算出的百分比差异在统计学上无统计学意义。 ）。原型设备可用于以良好的准确性评估疾病。

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