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Anthropometric measurements for assessing insulin sensitivity on patients with metabolic syndrome, sedentaries and marathoners

机译:人体测量法评估代谢综合征,久坐不动和马拉松运动员的胰岛素敏感性

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The diagnosis of low insulin sensitivity is commonly done through the HOMA-IR index, in which fasting insulin and glucose blood levels are evaluated. Insulin and blood glucose levels are used for insulin sensitivity assessment by surrogate methods (HOMA-IR, Matsuda, etc), but anthropometric measurements like body weight, height and waist circumference are not considered, even if these variables also are related to low insulin sensitivity and metabolic syndrome. In this study we evaluate the impact of anthropometric measurements on the HOMA-IR, Matsuda and Caumo indexes to estimate insulin sensitivity. Specifically, we compare insulin sensitivity indexes with and without the anthropometric measurements in their equations on three different groups: patients with metabolic syndrome, sedentaries and marathoners. Results show relationships between anthropometric variables and insulin sensitivity indexes. On the other hand, subjects are mapped differently for insulin sensitivity assessment when anthropometric variables are taken into account. In addition, subjects diagnosed with normal insulin sensitivity could be considered as having low insulin sensitivity when anthropometric variables are considered.
机译:胰岛素敏感性低的诊断通常通过HOMA-IR指数完成,该指数可评估空腹胰岛素和血糖水平。胰岛素和血糖水平可通过替代方法(HOMA-IR,Matsuda等)用于胰岛素敏感性评估,但不考虑人体测量指标,例如体重,身高和腰围,即使这些变量也与低胰岛素敏感性相关和代谢综合征。在这项研究中,我们评估了人体测量对HOMA-IR,Matsuda和Caumo指数的影响,以评估胰岛素敏感性。具体来说,我们将胰岛素敏感性指数与未进行人体测量的方程式在三个不同组中进行比较:代谢综合征,久坐不动和马拉松运动员。结果显示人体测量学变量与胰岛素敏感性指数之间的关系。另一方面,当考虑人体测量学变量时,对受试者进行不同的映射以进行胰岛素敏感性评估。另外,当考虑人体测量学变量时,被诊断为具有正常胰岛素敏感性的受试者可以被认为具有低胰岛素敏感性。

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