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首页> 外文会议>Annual conference of the International Society of Exposure Science >Re-thinking strategies for improving exposure assessments
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Re-thinking strategies for improving exposure assessments

机译：重新考虑策略以改善暴露评估

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In order that chemicals risk assessments can be seen to be relevant and reliable, they must be able to effectively undertake both hazard and exposure assessment. However, the fact that the use of many chemicals is widespread can be associated with a high degree of uncertainty in the ability to accurately predict exposure. This uncertainty can undermine steps being taken to improve hazard assessment. The introduction of tiered approaches to exposure assessment provides opportunities for improving the relevance and reliability of exposure assessments through the efficient and targeted acquisition and application of key information on exposure parameters. Strategy Development Ensuring reliable and relevant exposure assessments not only demands that the exposure model is accurate but also requires that the determinants used as the basis of predictions reflect real world conditions. This consideration is particularly important when the determinants are factors that enable users of chemicals to determine how best to reduce exposures, such as those which may be communicated to workers and consumers within safety data sheets and labels. Within Europe, following the introduction of REACH, suppliers and users of chemicals have begun to more widely share such information, but its provision could become piecemeal unless suitably targeted and coordinated. The presentation will examine the considerations necessary for implementing effective strategies for collecting exposure information which are summarised in the figure . Particular attention will be paid to recent initiatives aimed at securing refined exposure information for worker and consumer assessments. Conclusion Recent developments aimed at structuring how information on exposure determinants might be collected by suppliers and users of chemicals provide opportunities for ensuring that exposure assessments are relevant and accurate. Implementing suitably coordinated approaches across these groups should avoid any tendency for the information to become piecemeal or deficient.
机译：为了使化学品风险评估被认为是相关和可靠的，它们必须能够有效地进行危害评估和暴露评估。但是，广泛使用多种化学药品这一事实可能与准确预测接触能力的高度不确定性有关。这种不确定性可能破坏正在采取的改进危害评估的步骤。暴露评估的分层方法的引入，通过有效，有针对性地获取和应用有关暴露参数的关键信息，为改善暴露评估的相关性和可靠性提供了机会。战略发展确保可靠和相关的暴露评估不仅要求暴露模型准确，而且要求用作预测基础的决定因素能反映现实情况。当决定因素是使化学品使用者能够确定如何最好地减少暴露的因素时，例如，可以在安全数据表和标签中传达给工人和消费者的那些因素，这一考虑尤其重要。在欧洲，引入REACH之后，化学品的供应商和用户已开始更广泛地共享此类信息，但是除非适当地加以针对性和协调，否则其提供的内容可能会变得零碎。该演示文稿将探讨实施有效的收集暴露信息策略的必要注意事项，图中总结了这些信息。将特别关注旨在确保为工人和消费者评估提供精炼的暴露信息的最新举措。结论结论最近的发展旨在构建如何由化学品的供应商和使用者收集有关暴露决定因素的信息，这为确保暴露评估是相关且准确的提供了机会。在这些群体之间实施适当协调的方法应避免任何信息变得零碎或不足的趋势。

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