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A balanced signal generator for lab on chip dielectrophoresis (DEP) levitation techniques

机译:用于芯片上电介电泳(DEP)悬浮技术的平衡信号发生器

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Dielectrophoresis (DEP) is the phenomenon where a force is exerted on a particle when a non-uniform electric field is applied. It's commonly used in separating cancer cells from healthy cells or separating different strains of bacteria. DEP requires 2 perfectly out of phase signals with matched amplitude for controlling the electrical field. This paper presents a low power balanced signal generator based on the operational floating current conveyor (OFCC) for the use in lab-on-chips that use DEP levitation. The OFCC is a versatile analog current mode building block. The circuit is designed using standard TSMC 90 nm CMOS technology. The circuit consumes 11 μW from a 0.4 V single supply. The total chip area is 0.053 mm2. The generator outputs 2 signals with 0.03 dB difference in amplitude and 5 degrees in phase at 1 MHz. Post layout simulation show that the circuit provides a promising solution for Lab-on-Chip using DEP levitation techniques.
机译:介电泳(DEP)是当施加不均匀电场时在粒子上施加力的现象。它通常用于从健康细胞中分离癌细胞或分离不同菌株的细菌。 DEP需要2个完全不同相且振幅匹配的信号来控制电场。本文提出了一种基于可操作浮动电流传送器(OFCC)的低功率平衡信号发生器,该信号发生器可用于使用DEP悬浮的芯片实验室。 OFCC是一种通用的模拟电流模式构建块。该电路是使用标准的台积电90 nm CMOS技术设计的。该电路从0.4 V单电源消耗的电流为11μW。芯片总面积为0.053 mm2。发生器在1 MHz时输出2个信号,它们的振幅差为0.03 dB,相位为5度。布局后仿真表明,该电路使用DEP悬浮技术为片上实验室提供了有希望的解决方案。

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