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3D-Printed Biodegradable Polyester Tissue Scaffolds for Cell Adhesion

机译:用于细胞粘附的3D打印的可生物降解聚酯组织支架

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Synthesis of a novel PTEGA dimethacrylate, characterization of photocured films, initial 3D printing, and cell viability is reported for the first time. These photocured and extracted films demonstrated significantly improved MDA-MB-231 cell viability at 1 day and 7 days as compared to non-tissue culture treated polystyrene. These cells also exhibited a healthy cell morphology, as observed by ESEM. Finally, the suitability of this new polyester oligo-mer for 3D printing was demonstrated with the printing of a cylinder, which models the endothelial tissue target application. These results indicate the potential for 3D-printed polyesters in a wide range of biological applications.
机译:首次报道了新型PTEGA二甲基丙烯酸酯的合成,光固化膜的表征,初始3D打印和细胞活力。与未组织培养处理的聚苯乙烯相比,这些光固化和提取的膜在1天和7天时显示出MDA-MB-231细胞活力的显着改善。如通过ESEM观察到的,这些细胞还表现出健康的细胞形态。最后,通过圆柱体的印刷证明了这种新型聚酯低聚物对3D打印的适用性,该圆柱体可模拟内皮组织目标应用。这些结果表明3D打印聚酯在广泛的生物学应用中具有潜力。

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