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首页> 外文会议>International IEEE/EMBS Conference on Neural Engineering >Characterization of retinal tissue and vitreous humor with Electrical Impedance Spectroscopy
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Characterization of retinal tissue and vitreous humor with Electrical Impedance Spectroscopy

机译：用电阻抗谱表征视网膜组织和玻璃体液

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摘要

Electrical impedance spectroscopy is used to study the retina and the vitreous humor which can help in designing retinal stimulation experiments. Electrical stimulation of retina is done to artificially stimulate retinal neurons for restoring vision in blind patients. The stimulus is given through microelectrodes which are placed over the retina. Since retina is an inhomogeneous conductive medium with ionic species as charge carriers, electrical characterization of the retina as well as the tissue interface is required. Vitreous humor comes in between tissue and electrode which has properties different from that of retina. Change in vitreous properties can alter the experimental results for stimulation of the retina. Thus calculation of electrical properties of both vitreous and retinal tissue are necessary for designing of stimulus parameters. Goat retina is used in this study for characterization which can help in further using this animal in stimulation experiments. It has been found that the RGC side of isolated retina has lower resistance to current flow compared to the photoreceptor side. It has also been found that changes in the vitreous properties that might affect the tissue stimulation parameters can be measured through impedance spectroscopy.
机译：电阻抗光谱法用于研究视网膜和玻璃体液，可帮助设计视网膜刺激实验。进行视网膜电刺激是为了人工刺激视网膜神经元，以恢复盲人的视力。通过放置在视网膜上方的微电极来提供刺激。由于视网膜是具有离子物质作为电荷载体的不均匀导电介质，因此需要对视网膜以及组织界面进行电学表征。玻璃体液进入组织和电极之间，其性质不同于视网膜。玻璃体性质的改变可以改变刺激视网膜的实验结果。因此，玻璃体和视网膜组织的电学特性的计算对于设计刺激参数是必要的。山羊视网膜在本研究中用于表征，可以帮助进一步在刺激实验中使用该动物。已经发现，与感光体侧相比，孤立的视网膜的RGC侧对电流的阻力较低。还发现可以通过阻抗光谱法测量可能影响组织刺激参数的玻璃体性质的变化。

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