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The application of model-based systems engineering to the practice of clinical medicine

机译：基于模型的系统工程在临床医学实践中的应用

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Humanity is currently facing an unprecedented chronic disease burden. Healthcare needs have significantly shifted from treating acute to treating chronic conditions. Chronic diseases tend to involve multiple factors with complex interactions between them evidenced by the continually growing medical knowledge base. The health profession requires the ability to manage this rapidly deepening knowledge base to assimilate the lessons from research and clinical care experience by systematically capturing, assessing and translating it into the highest level of reliable care. A more systems approach to practicing medicine exists and is referred to as functional medicine. It takes into account the many subsystems in the human body and their many interactions. Although the science behind treating the patient as a system exists, the application of systems tools and techniques have not been utilized. It is only natural to begin to formalize the systems thinking using the established tools from the systems engineering field. Specifically, this paper is the first to contribute to the need for systems tools in the practice of clinical medicine and includes an example application of model-based systems engineering to clinical medicine.
机译：人类目前正面临着前所未有的慢性疾病负担。医疗保健需求已从急性治疗转移到慢性疾病治疗。慢性病往往涉及多种因素，它们之间相互作用复杂，这由不断增长的医学知识基础证明。卫生专业人士需要具备管理这一迅速加深的知识库的能力，以通过系统地获取，评估并将其转化为最高水平的可靠护理来吸收研究和临床护理经验中的教训。存在实践医学的更多系统方法，并且被称为功能医学。它考虑了人体中许多子系统及其相互作用。尽管存在将患者视为系统的科学，但尚未利用系统工具和技术的应用。很自然地开始使用系统工程领域中已建立的工具来使系统思想形式化。具体来说，本文是第一个为临床医学实践中的系统工具需求做出贡献的论文，其中包括基于模型的系统工程在临床医学中的示例应用。

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