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首页> 外文会议>International Conference on Solid-State Sensors, Actuators and Microsystems >Photonic lab-on-a-chip device with UV light responsive smart surfaces
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Photonic lab-on-a-chip device with UV light responsive smart surfaces

机译：具有对紫外线敏感的智能表面的光子芯片实验室设备

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A novel lab-on-a-chip (LoC) device based on the combination of an optofluidic component and a polymeric substrate with a smart surface reacting on UV light is presented for the first time. In the dark or under visible light, the surface containing an enzyme fragment is almost inert and visible (VIS) light (i.e. @ 635 nm) propagating through the optofluidic device is mostly unaffected. When the device is exposed to UV light, the smart surface consisting of spiropyran-functionalized polymer brushes reacts with increased hydrophilicity. As a consequence, the polymer brushes are swelling, enhancing the access of reagents to the enclosed enzyme. The enzymatic reaction yields a blue reaction product causing increased absorbance at 635 nm. Here, we demonstrate both the integration of the optofluidic component and the smart surface into a photonic LoC device, its behavior and performance and the reversible nature of the UV activation.
机译：首次介绍了基于邻接物体组分和具有智能表面反应的硅化物质组分和聚合物基板的组合的新型实验室芯片（LOC）装置，首次呈现在UV光上的智能表面反应。在黑暗或可见光下，含有酶片段的表面几乎是惰性的并且可见（Vis）光（即635nm）通过Optof流体装置传播主要是不受影响的。当器件暴露于UV光时，由螺旋吡喃官能化聚合物刷组成的智能表面与增加的亲水性反应。结果，聚合物刷是溶胀的，增强试剂的进入到封闭的酶。酶反应产生蓝色反应产物，导致635nm的吸光度增加。在这里，我们证明了优化成分和智能表面的整合，将其行为和性能以及UV激活的可逆性。

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