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首页> 外文会议>International Conference on Solid-State Sensors, Actuators and Microsystems >Contact fusion of droplets patterned on opposing plates for cellular transportation and medium exchange for hanging droplet cell culture
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Contact fusion of droplets patterned on opposing plates for cellular transportation and medium exchange for hanging droplet cell culture

机译：在相对板上构图的液滴的接触融合，用于细胞运输和用于悬浮液滴细胞培养的培养基交换

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摘要

This paper presents cellular transportation from a droplet on an originator plate to a droplet on an opposing receiver plate by contact fusion of the two droplets. This technique can be applied to the exchange of medium, drug delivery, and in situ characterization for hanging droplet cell cultures. Our study allows patterning of droplet arrays on the receiver plate in ways that facilitate contact fusion of droplets to occur at their locations on the receiver plate. Photoresponsive wettability of titanium dioxide patterns was used for patterning of the droplets. Hanging droplet cell culture successfully demonstrated exchange of medium via the contact fusion of droplets. This paper reports the proposed strategy, droplet array formation, cellular transportation, and liquid transportation for exchange of the medium and drug delivery.
机译：本文介绍了通过两个液滴的接触融合，从原始板上的液滴到相对的接收板上的液滴的细胞运输过程。这项技术可以应用于培养基的交换，药物输送和悬挂液滴细胞培养的原位表征。我们的研究允许以易于在液滴在接收板上的位置发生接触熔合的方式在接收板上形成液滴阵列的图案。二氧化钛图案的光响应性可湿性用于液滴的图案化。悬挂液滴细胞培养成功地证明了通过液滴的接触融合进行培养基的交换。本文报道了所提出的策略，液滴阵列形成，细胞运输和液体运输，以交换培养基和药物。

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