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Role of macrophage-produced cytokines by stimulation of calcium phosphate ceramics in the material-mediated #osteoblastic differentiation of mesenchymal stem cells

机译:通过刺激磷酸钙陶瓷巨噬细胞产生的细胞因子在间质干细胞的材料介导的#成骨细胞分化中的作用

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Conclusions: Osteoinduction of CaP ceramics might be related to the material-aroused immune responses. CaP ceramics stimulate the signalling protein molecules secretion of macrophages, which could help recruit MSCs and osteoblastic differentiation of MSCs in the ceramics. Besides the phase composition, some other factors including microstructure and degradation etc. might affect the osteoinduction of CaP ceramics.
机译:结论:CaP陶瓷的成骨诱导可能与物质引起的免疫反应有关。 CaP陶瓷刺激巨噬细胞的信号蛋白分子分泌,这可能有助于在陶瓷中募集MSC和MSC的成骨细胞分化。除了相组成,其他一些因素,包括微观结构和降解等,可能会影响CaP陶瓷的骨诱导。

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