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Performance Assessment of a Dedicated Reflectance Pulse Oximeter in a Neonatal Intensive Care Unit

机译:新生儿重症监护病房专用反射脉搏血氧仪的性能评估

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The measurement of peripheral oxygen saturation (SpO2) in neonatal intensive care units (NICUs) poses a significant challenge. Motion artifacts due to the patient's limb motion induce many false alarms, which in turn cause an additional workload for the medical staff and anxiety for the parents. We developed a reflectance pulse oximeter dedicated to be placed at the patient's forehead, which is less prone to such artifacts. We trained our algorithms for SpO2 estimation on 8 adult healthy volunteers participating in a controlled desaturation study. We then validated our SpO2 monitoring system on 25 newborn patients monitored in an NICU. We further evaluated the versatility and resilience to low signal-to-noise ratios (SNR) of our solution by testing it on signals acquired in a low-perfusion region (upper right part of the chest) of our adult volunteers. We obtained an SpO2 estimation accuracy (Arms) of 1.9 % and 3.1 % at the forehead and the chest in our adult volunteers, respectively. These performances were obtained after automatic rejection of 0.1 % and 30.0 %, respectively, of low-SNR signals by our dedicated quality index. In the dataset recorded on newborn patients in the NICU, we obtained an accuracy of 3.9 % after automatic rejection of 11.7 % of low-SNR signals by our quality index. These analyses were carried out following the procedures suggested by the ISO 80601-2-61:2011 standard, which specifies a target Arms ≤ 4% for SpO2 monitoring applications. These promising results suggest that reflectance pulse oximeters can achieve clinically acceptable accuracy, while being placed at locations less sensitive to limb motion artifacts - such as the forehead - thereby reducing the amount of SpO2-related false alarms in NICUs.
机译:外周血氧饱和度(SpO 2 )在新生儿重症监护病房(NICU)中提出了重大挑战。由于患者肢体运动而引起的运动伪影会引起许多错误警报,进而给医护人员带来额外的工作量,并给父母带来焦虑。我们开发了一种专用于患者额头的反射式脉搏血氧仪,这种血氧仪不易出现此类伪影。我们为SpO训练了算法 2 参加对照去饱和研究的8位成人健康志愿者的估计值。然后,我们验证了SpO 2 在新生儿重症监护病房(NICU)中监测的25名新生儿患者的监测系统。我们通过对成年志愿者在低灌注区域(胸部右上部)获得的信号进行测试,从而进一步评估了我们解决方案对低信噪比(SNR)的多功能性和适应性。我们获得了SpO 2 估计精度(A rms 成年志愿者的前额和胸部的)分别为1.9%和3.1%)。这些性能是通过我们专用的质量指标分别分别自动剔除0.1%和30.0%的低SNR信号后获得的。在重症监护病房新生儿患者记录的数据集中,根据我们的质量指标,在自动拒绝11.7%的低SNR信号后,我们获得了3.9%的准确度。这些分析是按照ISO 80601-2-61:2011标准建议的程序进行的,该程序指定了目标A rms SpO≤4% 2 监视应用程序。这些有前途的结果表明,反射脉搏血氧仪可以放置在对肢体运动伪影不太敏感的位置(例如前额),同时可以达到临床可接受的精度,从而减少SpO的量。 2 与重症监护病房相关的错误警报。

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