首页> 外文会议>Society for Biomaterials annual meeting and exposition >Micronized Amnion/Chorion Delivery Promotes Mesenchymal Stem Cell Recruitment to the Supraspinatus Muscle After Rotator Cuff Injury
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Micronized Amnion/Chorion Delivery Promotes Mesenchymal Stem Cell Recruitment to the Supraspinatus Muscle After Rotator Cuff Injury

机译:微粒化的羊膜/绒毛膜递送促进肩袖损伤后间质干细胞募集至上睑肌。

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This study indicates that udHACM is able to recruit inflammatory and pro-healing cells to the supraspinatus muscle after severe rotator cuff injury. While there was recruitment of both Ml and M2-like macrophages by udHACM, these results are not significantly different from the number of these cells that were recruited due to injury only, which suggests that the material does not elicit an extreme pro-inflammatory response. Overall, the ability of udHACM to recruit MSCs to the muscle indicates that implantation of this material may be a promising method to promote muscle regeneration following rotator cuff injury, which is the subject of ongoing studies.
机译:这项研究表明,udHACM能够在严重的肩袖损伤后将炎性细胞和促愈合细胞募集到棘上肌。尽管udHACM同时募集了M1和M2样巨噬细胞,但是这些结果与仅由于损伤而募集的这些细胞的数量没有显着差异,这表明该物质不会引起极端的促炎反应。总体而言,udHACM将MSC募集到肌肉的能力表明,植入这种材料可能是促进肩袖损伤后肌肉再生的有前途的方法,这是正在进行的研究的主题。

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