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首页> 外文会议>International IEEE/EMBS Conference on Neural Engineering >Objective levodopa response in Parkinson's disease: A study within the medical consultation using an RGB-D camera (Kinect®)
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Objective levodopa response in Parkinson's disease: A study within the medical consultation using an RGB-D camera (Kinect®)

机译：帕金森氏病的客观左旋多巴反应：使用RGB-D相机（Kinect®）在医学会诊中进行的一项研究

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Background: Since 1988, one of the most relevant criteria that support diagnosis of Parkinson Disease (PD) is the response to levodopa. Levodopa effect is evaluated using clinical scales such (MDS-UPDRS). Although this approach is informative its assessment is highly subjective. Objectives: quantify the motor response to levodopa in patients with Parkinson's disease using a portable and inexpensive RGB-D camera (Kinect) Methods: 11 PD patients were included. Descriptive analysis were used for clinical variables. Spearmańs rank correlation was used to correlate the age and the gait variables. Wilcoxon matched-pairs signed-rank test was used for the gait variables comparison between ON and OFF states. Results: In ON state PD patients showed increments in global speed [p=0.007], ankle speed [p<;0.001], ankle stride length [p=0.001], arm swing speed [p=0.008], and arm swing magnitude [p=0.014], these results slightly changed when the sample was analyzed taking into account the individual behavior of each limb. In comparison with the upper limbs, levodopa response was more uniform in the lower limbs. Conclusion: As expected, in ON state PD patients improve their speed and their limbs range of movement during gait. Levodopa response can be measured within the medical consultation using a RGB-D camera.
机译：背景：自1988年以来，对左旋多巴的反应是支持诊断帕金森氏病（PD）的最相关标准之一。左旋多巴的疗效可通过临床量表（MDS-UPDRS）进行评估。尽管这种方法提供了很多信息，但其评估是非常主观的。目的：使用便携式廉价的RGB-D相机（Kinect）来量化帕金森氏病患者对左旋多巴的运动反应。方法：纳入11名PD患者。描述性分析用于临床变量。 Spearmańs等级相关性用于关联年龄和步态变量。使用Wilcoxon配对对有符号秩检验对ON和OFF状态之间的步态变量进行比较。结果：在ON状态下，PD患者的整体速度[p = 0.007]，脚踝速度[p <; 0.001]，脚踝步幅长度[p = 0.001]，手臂摆动速度[p = 0.008]和手臂摆动幅度[ p = 0.014]，在分析样本时，考虑到每个肢体的个体行为，这些结果略有变化。与上肢相比，左下肢左旋多巴反应更为均匀。结论：如预期的那样，在ON状态下，PD患者在步态中可以提高速度和四肢​​的活动范围。左旋多巴反应可以在医疗咨询中使用RGB-D摄像机进行测量。

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