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Synergistic Effects of Functional Additives on the Physico-Mechanical and Biological Properties of Poly(L-lactic acid) Composites for Cardiovascular Implant Applications

机译：功能性添加剂对用于心血管植入物的聚（L-乳酸）复合材料的物理机械和生物学特性的协同效应

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Bulk modification of PLLA with the functional additives of thermal stabilizer and plasticizer synergistically enhanced thermal stability and mechanical properties of PLLA. In addition, further incorporation of MH nanoparticles into bulk modified PLLA significantly reduced the in vitro inflammatory response due to efficient neutralization of acidic byproducts of degraded PLLA by MH nanoparticles. This work suggests a new platform in designing a biodegradable cardiovascular implants including stents with improved thermal and mechanical properties and reduced inflammatory response.

机译：用热稳定剂和增塑剂的功能性添加剂对PLLA进行整体改性，可协同增强PLLA的热稳定性和机械性能。另外，由于MH纳米颗粒有效地中和了降解的PLLA的酸性副产物，因此将MH纳米颗粒进一步掺入本体改性的PLLA中显着降低了体外炎症反应。这项工作为设计可生物降解的心血管植入物提供了一个新的平台，其中包括具有改善的热和机械性能以及降低的炎症反应的支架。

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《Society for Biomaterials annual meeting and exposition》|2019年|464-464|共1页
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Eun Young Kang; Bogyu Choi; Wooram Park; Ik Hwan Kim; Dong Keun Han;
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1. One step bulk modification of poly(L-lactic acid) composites with functional additives to improve mechanical and biological properties for cardiovascular implant applications [J] . Kang Eun Young, Choi Bogyu, Park Wooram, Colloids and Surfaces, B. Biointerfaces . 2019,第期

机译：具有功能添加剂的聚（L-乳酸）复合材料的一步大批量改性，提高心血管植入应用的机械和生物学性能
2. Effects of poly(L-lactide-ε-caprolactone) and magnesium hydroxide additives on physico-mechanical properties and degradation of poly(L-lactic acid) [J] . Eun Young Kang, Eugene Lih, Ik Hwan Kim, Biomaterials Research . 2016,第1期

机译：聚（L-丙交酯-ε-己内酯）和氢氧化镁添加剂对聚（L-乳酸）的物理力学性能和降解的影响
3. Poly(L-lactic acid)/Boron Nitride Nanocomposites: Influence of Boron Nitride Functionalization on the Properties of Poly(L-lactic acid) [J] . Rosely C. V. Sijla, Shaiju P., Gowd E. Bhoje The journal of physical chemistry, B. Condensed matter, materials, surfaces, interfaces & biophysical . 2019,第40期

机译：聚（L-乳酸）/氮化硼纳米复合材料：氮化硼官能化对聚（L-乳酸）性能的影响
4. Synergistic Effects of Functional Additives on the Physico-Mechanical and Biological Properties of Poly(L-lactic acid) Composites for Cardiovascular Implant Applications [C] . Eun Young Kang, Bogyu Choi, Wooram Park, Society for Biomaterials annual meeting and exposition . 2019

机译：功能性添加剂对心血管植入应用的聚（L-乳酸）复合材料物理 - 机械和生物学性能的协同作用
5. An in vitro study of the elastic property loss of poly(L-lactic acid), PLLA, filaments undergoing hydrolysis in tissue engineering applications. [D] . Russell, Stacey Lee. 2004

机译：在组织工程应用中进行水解的聚L-乳酸PLLA长丝的弹性损失的体外研究。
6. Effects of poly(L-lactide-ε-caprolactone) and magnesium hydroxide additives on physico-mechanical properties and degradation of poly(L-lactic acid) [O] . Eun Young Kang, Eugene Lih, Ik Hwan Kim, 2016

机译：聚（L-丙交酯-ε-己内酯）和氢氧化镁添加剂对聚（L-乳酸）的物理力学性能和降解的影响
7. Effects of poly(L-lactide-ε-caprolactone) and magnesium hydroxide additives on physico-mechanical properties and degradation of poly(L-lactic acid) [O] . Eun Young Kang, Eugene Lih, Ik Hwan Kim, 2016

机译：聚（L-丙交酯-ε-己内酯）和氢氧化镁添加剂对聚（L-乳酸）的物理力学性能和降解的影响
8. Precipitation of Poly(L-Lactic Acid) and Composite Poly(L-Lactic Acid)-PyreneParticles by Rapid Expansion of Supercritical Solutions [R] . Tom, J. W., Debenedetti, P. G. 1994

机译：超临界溶液快速膨胀沉淀聚L-乳酸和复合聚L-乳酸 - 苯乙烯颗粒

Synergistic Effects of Functional Additives on the Physico-Mechanical and Biological Properties of Poly(L-lactic acid) Composites for Cardiovascular Implant Applications

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