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Interplay Between Degradability and Integrin Signaling on Mesenchymal Stem Cell Function within Porous Poly(ethylene glycol) Microgel Scaffolds

机译：多孔聚（乙二醇）微凝胶支架内的间充质干细胞功能的降解性和整合素信号之间的相互作用。

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We found that cell-mediated degradation is critical to generate more space within microgel scaffolds for long-term hMSC proliferation. These degradable scaffolds can also contribute to integrin signaling pathway activation for angiogenesis and osteogenesis. Future studies will apply these results to the development of 3D cell-laden microgel scaffolds for bone regeneration.

机译：我们发现细胞介导的降解对于长期hMSC增殖在微凝胶支架内产生更多空间至关重要。这些可降解的支架还可以促进整联蛋白信号通路的激活，从而促进血管生成和成骨。未来的研究会将这些结果应用于开发3D细胞载有微凝胶的骨再生支架。

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《Society for Biomaterials annual meeting and exposition》|2019年|253-253|共1页
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Shangjing Xin; Carl Gregory; Daniel Alge;
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1. Interplay between degradability and integrin signaling on mesenchymal stem cell function within poly(ethylene glycol) based microporous annealed particle hydrogels [J] . Xin Shangjing, Gregory Carl A., Alge Daniel L. Acta biomaterialia . 2020,第期

机译：聚（乙二醇）微孔退火颗粒水凝胶中间充质干细胞功能的降解性和整合素信号的相互作用
2. Chondrogenic differentiation potential of human mesenchymal stem cells photoencapsulated within poly(ethylene glycol)-arginine-glycine-aspartic acid-serine thiol-methacrylate mixed-mode networks. [J] . Salinas CN, Cole BB, Kasko AM, Tissue engineering . 2007,第5期

机译：光包裹在聚（乙二醇）-精氨酸-甘氨酸-天冬氨酸-丝氨酸硫醇-甲基丙烯酸酯混合模式网络中的人间充质干细胞的软骨分化潜能。
3. Chondrogenic Differentiation Potential of Human Mesenchymal Stem Cells Photoencapsulated within Poly(Ethylene Glycol)–Arginine-Glycine-Aspartic Acid-Serine Thiol-Methacrylate Mixed-Mode Networks [J] . Chelsea N. Salinas Brook B. Cole Andrea M. Kasko Kristi S. Anseth Tissue Engineering . 2007,第5期

机译：光包裹在聚乙二醇-精氨酸-甘氨酸-天冬氨酸-丝氨酸-甲基丙烯酸甲酯混合模式网络中的人间充质干细胞的软骨分化潜能
4. Interplay Between Degradability and Integrin Signaling on Mesenchymal Stem Cell Function within Porous Poly(ethylene glycol) Microgel Scaffolds [C] . Shangjing Xin, Carl Gregory, Daniel Alge Society for Biomaterials annual meeting and exposition . 2019

机译：多孔聚（乙二醇）微凝胶支架中间充质干细胞功能的降解性与整合素信号的相互作用
5. Integrin Binding Peptide-Functionalized Poly(Ethylene Glycol) Hydrogels for Understanding the Role of Matricellular Effects on VIC Phenotype and Tissue Deposition. [D] . Gould, Sarah. 2013

机译：整合素结合肽功能化的聚乙二醇乙二醇水凝胶，用于了解母细胞对VIC表型和组织沉积的作用。
6. Poly(3-hydroxybutyrate)/poly(ethylene glycol) scaffolds with different microstructure: the effect on growth of mesenchymal stem cells [O] . A. P. Bonartsev, I. I. Zharkova, V. V. Voinova, 2018

机译：具有不同微观结构的聚3-羟基丁酸酯/聚乙二醇支架：对间充质干细胞生长的影响
7. Electrospun Poly(l-lactide)/Poly(ethylene glycol) Scaffolds Seeded with Human Amniotic Mesenchymal Stem Cells for Urethral Epithelium Repair [O] . Xiaokui Lv, Qianping Guo, Fengxuan Han, 2016

机译：电喷聚（L-丙交酯）/聚（乙二醇）支架植入人羊膜间充质干细胞用于尿道上皮修复

Interplay Between Degradability and Integrin Signaling on Mesenchymal Stem Cell Function within Porous Poly(ethylene glycol) Microgel Scaffolds

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