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Combinatorial Screening of 3D Printable Bioinks for Cartilage Repair

机译:用于软骨修复的3D可打印生物墨水的组合筛选

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NorHA hydrogels were synthesized with various compositions and 3D printed via in situ photo-crosslinking. The process was cytocompatible and used to print cell-laden hydrogels for cartilage engineering. The employment of combinatorial hydrogels permitted identification of bioinks with optimal microenvironments towards the formation of neocartilage. Ultimately, this approach will be useful towards designing patient-specific implants for the treatment of focal defects and eventually osteoarthritis.
机译:合成具有不同组成的NorHA水凝胶,并通过原位光交联3D打印。该过程具有细胞相容性,可用于打印载有软骨的细胞的水凝胶。组合水凝胶的使用允许鉴定具有最佳微环境的生物墨水,以形成新的软骨。最终,这种方法将有助于设计针对患者的植入物,以治疗局灶性缺陷和最终的骨关节炎。

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