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首页> 外文会议>Engineering in Medicine and Biology Society, 1998. Proceedings of the 20th Annual International Conference of the IEEE >Transcranial magnetic stimulation combined with EEG: a new brain imaging tool
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Transcranial magnetic stimulation combined with EEG: a new brain imaging tool

机译：经颅磁刺激结合脑电图：一种新的脑成像工具

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The authors have developed frameless stereotaxy for applying TMS to a given spot in the brain as determined by MRI. They have used high-resolution EEG (HR-EEG) with 60 channels to monitor and locate the TMS-induced activity so that excitability of the different portions of the cortex and connectivity between different areas can be mapped reliably. By using dipole modeling and minimum-norm estimation, the authors have observed both ipsi- and contralateral spreading of neuronal activity after a TMS pulse. They have also demonstrated that TMS stimulation can affect the dynamics of sensory evoked auditory and somatosensory potentials. They expect that the combination of TMS and HR-EEG will offer a powerful tool for basic neuroscience and for clinical diagnosis, for example in the assessment of brain connectivity in patients suffering from neurodegenerative diseases or head injuries.
机译：作者已经开发出无框架立体定位技术，可以将TMS应用到MRI所确定的大脑中给定位置。他们使用了具有60个通道的高分辨率脑电图（HR-EEG）来监视和定位TMS诱导的活动，从而可以可靠地绘制皮层不同部分的兴奋性以及不同区域之间的连通性。通过使用偶极建模和最小范数估计，作者已经观察到TMS脉冲后神经元活动的同侧和​​对侧扩展。他们还证明了TMS刺激可以影响感觉诱发听觉和体感电位的动力学。他们希望TMS和HR-EEG的结合将为基础神经科学和临床诊断提供强大的工具，例如用于评估神经退行性疾病或头部受伤的患者的大脑连通性。

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