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首页> 外文会议>Engineering in Medicine and Biology Society, 2003. Proceedings of the 25th Annual International Conference of the IEEE >Unitary premotor drives and modular reflex primitives in frog spinal cord
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Unitary premotor drives and modular reflex primitives in frog spinal cord

机译：青蛙脊髓中的整体前运动驱动和模块化反射原语

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摘要

Modular organization of reflexes and premotor drives in frog spinal cord can be revealed in a number of ways. Isometric force-field measurements, electromyogram decomposition with statistical methods, and direct reflex manipulation all support a small number of elements supporting spinal behaviors. The central neural circuits that support the modules indicated by these methods are not well understood. A current focus of our laboratory is to begin to examine activity patterns that support modular common drives. To examine activity we are using a Bionic Technologies Cerebus 128 channel system with real time (1KHz 1ms resolution) delivery of up to 2 resolved spikes spikes per channel. Neuralynx Cyborg drives, microwire, and tetrodes are being tested for recording with this system. Activity is elicited by reflex stimulation to induce wipe movements or muscle vibration. We are also testing activity induction by photolytic uncaging of glutamate in the preparation, a technique with the advantage of no electrical artefact but perhaps reduced temporal precision. If recruited by microstimulation or other means a modular spinal circuitry may in the future support powerful neuroprosthetic designs.
机译：青蛙脊髓中反射和前运动驱动的模块化组织可以通过多种方式揭示。等距力场测量，采用统计方法的肌电图分解以及直接反射操作都支持少量支持脊柱行为的元素。支持这些方法所指示的模块的中央神经回路还没有被很好地理解。我们实验室的当前重点是开始研究支持模块化通用驱动器的活动模式。为了检查活动，我们使用了Bionic Technologies Cerebus 128通道系统，该系统实时（1KHz 1ms分辨率）提供每个通道最多2个已解决的尖峰脉冲。正在使用该系统对Neuralynx Cyborg驱动器，微线和四极管进行记录测试。通过反射刺激引起活动，以引起擦拭运动或肌肉振动。我们还在通过制剂中谷氨酸的光解开封来测试活性诱导，该技术的优点是没有电伪像，但可能降低了时间精度。如果通过微刺激或其他方式募集，则模块化的脊柱电路将来可能会支持强大的神经假体设计。

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