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Effect of Apatite Nanoparticles on Remineralization of the Demineralized Human Dentin

机译:磷灰石纳米颗粒对脱矿质人牙本质矿化的影响

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The aim of this study was to evaluate the remineralizing potential of demineralized human dentin treated with Y/HA nanoparticles (doping Y with 5mol %) and HA nanoparticles suspension and whether dentin could be remineralized by HA. Human crown dentin was demineralized with EDTA for 4 hours, and then subjected to remineralization condition. The ability of these matrices to remineralize was determined by SEM, AFM and calcium levels in the remineralized tissue were measured by atomic energy spectrum analysis. The results showed that Y/HA and HA nanoparticles remineralized the demineralized dentin surface; these demineralized matrices treated with Y/HA nanoparticles remineralized to a greater extent than those treated HA nanoparticles. The differences in both the quality and quantity, as defined by Yttrium iones leading to changes in characterization of the apatite crystals might be important in effecting the ability of this tissue to remineralize. This work suggested that apatite nanoparticles caused remineralization of dentin and the yttrium ions substituted in the apatite structure might enhance their remineralization potential.
机译:本研究的目的是评估用Y / Ha纳米颗粒(用5mol%)和Ha纳米颗粒悬浮液处理的脱耳化人牙本肽的再矿化潜力,HA纳米颗粒悬浮液以及牙本质是否可以通过HA再归化。人冠牙本质用EDTA脱矿4小时,然后进行再矿化条件。通过原子能谱分析测量综合组织中的SEM,AFM和钙水平测定这些基质以再矿化的能力。结果表明,y / ha和ha纳米颗粒再矿化了脱矿质的牙本质表面;这些脱矿质用Y / HA纳米颗粒处理的脱矿质基质在比那些处理的HA纳米颗粒更大程度地结转。由钇离子定义的质量和量的差异导致磷灰石晶体表征的变化可能是重要的,这对于这种组织再矿化的能力是重要的。这项工作表明,磷灰石纳米颗粒引起了牙本质的再矿化,并且在磷灰石结构中取代的钇离子可能会增强它们的再矿化潜力。

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