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首页> 外文会议>Materials research : Eco/enviromental materials energy materials magnesium, aerospace materials and biomaterials for medical application >Gradient Rare-earths Bioceramic Composite Coating Fabricated by Wide-band Laser Cladding And Its Bioactivity
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Gradient Rare-earths Bioceramic Composite Coating Fabricated by Wide-band Laser Cladding And Its Bioactivity

机译：宽带激光熔覆制备梯度稀土生物陶瓷复合涂层及其生物活性

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摘要

A gradient bioceramic composite coating was prepared by wide-band laser cladding technique on TC4 alloy surface. The influence of rare earths oxide CeO_2 on microstructure of bioceramic coating was studied. The experimental results indicated that CeO2 plays an important role in inducing HA + β-TCP formation. There is almost no HA+β-TCP in bioceramic coating without CeO_2, When CeO_2 content is higher than 0.2 wt.%, the amount of HA+P-TCP catalyzed by CeO_2 gradually increases. The amount of HA+β-TCP becomes largest when CeO_2 content is up to 0.4wt%. However, when CeO_2 content ranges from 0.6 wt.% to 0.8 wt.%, the amount of synthesizing HA+β-TCP conversely goes down. Through cell culture experiment in vitro, the effect of bioceramic coating with different CeO_2 contents on the expression of characteristic protein is investigated. The results show that the largest amount of expression of hydroxyproline(Hyp) at 2d and alkaline phosphatase(ALP) at 6d on coating is complied with 0.4wt.% CeO_2, The result indicates that bioactivity of bioceramic coating is dependent on the amount of HA + β-TCP catalyzed by different CeO_2 contents.
机译：通过宽带激光熔覆技术在TC4合金表面制备了梯度生物陶瓷复合涂层。研究了稀土氧化物CeO_2对生物陶瓷涂层微观结构的影响。实验结果表明，CeO2在诱导HA +β-TCP形成中起重要作用。没有CeO_2的生物陶瓷涂层中几乎没有HA +β-TCP，当CeO_2含量高于0.2 wt。％时，CeO_2催化的HA + P-TCP量逐渐增加。当CeO_2含量达到0.4wt％时，HA +β-TCP的量最大。然而，当CeO_2的含量在0.6重量％至0.8重量％的范围内时，HA +β-TCP的合成量反而下降。通过体外细胞培养实验，研究了不同CeO_2含量的生物陶瓷涂层对特征蛋白表达的影响。结果表明，在0.4d。％的CeO_2条件下，涂层上第2d的羟脯氨酸（Hyp）和碱性磷酸酶（ALP）的表达量最大，表明生物陶瓷涂层的生物活性取决于HA的量。 CeO_2的不同含量催化了+β-TCP。

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