首页> 外文会议>2010 IEEE International Conference on Bioinformatics and Biomedicine Workshops >Genome-wide DNA methylation analysis in tumor and normal tissues from lung squamous cell carcinoma and serous cystadenocarcinoma
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Genome-wide DNA methylation analysis in tumor and normal tissues from lung squamous cell carcinoma and serous cystadenocarcinoma

机译:肺鳞状细胞癌和浆液性囊腺癌的肿瘤和正常组织中全基因组DNA甲基化分析

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Genome-wide DNA methylation was analysed in tumor and normal tissues. HOXA9, HOXD4, TBX4 were found to be hypermethylated in tumor tissues whereas PAX4 was found to be hypermethylated in normal tissues. HOXD4 and TBX4 are suggested to be potent tumor suppressor genes or tumor suppressor associated genes.
机译:在肿瘤和正常组织中分析了全基因组DNA甲基化。发现HOXA9,HOXD4,TBX4在肿瘤组织中是高甲基化的,而PAX4在正常组织中是高甲基化的。 HOXD4和TBX4被认为是有效的抑癌基因或抑癌相关基因。

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