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Groundwater contamination by arsenic in of 24-Parganas district of West Bengal, India: A health risk

机译:印度西孟加拉邦24-Parganas地区砷对地下水的污染:健康风险

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Arsenic poisoning due to contaminated groundwater in West Bengal, India, has been thought to be limited to the Lower Ganga Plain (LGP). Skin lesions in villagers led us to evaluate arsenic exposure in the Moyna and Adrebok villages of 24 Porgana (s) West Bengal, India in the LGP where tube wells water was used for drinking water. Results of this investigation are indicated that the groundwater of Moyna and Adrebok villages have been severely affected by As (arsenic). Most of the tubewells exceeded Arsenic (As) concentration upper limit of Indian standard (50µg/L). Few people were affected by chronic bronchitis and whole body infection. The concentration of total arsenic in urine, hair, and nails has been proposed as an indicator of environmental exposure to arsenic. The positive associations between arsenic contents measured in the urine, hair, and nails indicate the degree of severity of arsenic exposure. The arsenic concentrations were found very high in nails with respect to hair and urine. However, arsenic concentrations in hair and urine were found very high. The correlation statistics indicate that the As concentrations in nails, hair and urine are highly correlated with the concentrations of ground water. The arsenic concentrations in urine, hair and nail were increased with the increase of age upto 42 year. The arsenic concentrations in hair and nail were increased more in compare to urine sample. Interestingly the arsenic concentration in urine, hair and nail were decreased from 43 year. As arsenic shows strong reactivity and therefore affinity towards thiol compounds, it preferentially accumulates in peripheral keratin-rich tissues such as skin, nail, and hair. The cases showed significantly higher arsenic accumulation in nail and hair. This load, coupled with the genetic idiosyncrasies of the arsenic-metabolizing genes, determines whether a particular individual will be susceptible to arsenic toxicity.
机译:据认为,印度西孟加拉邦因地下水污染而引起的砷中毒仅限于恒河下游平原(LGP)。村民的皮肤病变使我们评估了LGP中印度西孟加拉邦Porgana(s)24个Moyna和Adrebok村庄的砷暴露,那里的管井水用作饮用水。调查结果表明,Moyna和Adrebok村庄的地下水已受到砷(砷)的严重影响。大多数试管孔都超过了印度标准的砷(As)浓度上限(50µg / L)。很少有人受到慢性支气管炎和全身感染的影响。已提出尿液,头发和指甲中总砷的浓度可作为环境暴露于砷的指标。尿液,头发和指甲中的砷含量之间呈正相关关系,表明砷暴露的严重程度。发现指甲中的砷相对于头发和尿液的浓度非常高。然而,发现头发和尿液中的砷浓度很高。相关统计表明,指甲,头发和尿液中的砷浓度与地下水浓度高度相关。尿,头发和指甲中的砷浓度随着年龄的增长而增加,直至42岁。与尿液样品相比,头发和指甲中的砷浓度增加更多。有趣的是,尿液,头发和指甲中的砷浓度从43岁开始降低。由于砷具有很强的反应性,因此对硫醇化合物具有亲和力,因此砷优先积累在富含角蛋白的外围组织(如皮肤,指甲和头发)中。这些病例显示出指甲和头发中砷的蓄积明显更高。这种负荷,加上砷代谢基因的遗传特性,决定了特定个体是否易受砷毒性作用。

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